Metabolism Antibodies 2
Anti-GYS1 Antibody (CAB2519)
- SKU:
- CAB2519
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-GYS1 Antibody |
| Antibody SKU: | CAB2519 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human GYS1 (NP_002094.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, BT-474, Mouse heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human GYS1 (NP_002094.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LLPV DYEE FVRG CHLG VFPS YYEP WGYT PAEC TVMG IPSI STNL SGFG CFME EHIA DPSA YGIY ILDR RFRS LDDS CSQL TSFL YSFC QQSR RQRI IQRN RTER LSDL LDWK YLGR YYMS ARHM ALSK AFPE HFTY EPNE ADAA QGYR YPRP ASVP PSPS LSRH SSPH QSED EEDP RNGP LEED GERY DEDE EAAK DRRN IRAP EWPR RASC TSST SGSK RNSV DTAT SSSL STPS EPLS PTSS LGEE RN |
| Gene ID: | 2997 |
| Uniprot: | P13807 |
| Cellular Location: | |
| Calculated MW: | 76kDa/83kDa |
| Observed MW: | 100kDa |
| Synonyms: | GYS1, GSY, GYS |
| Background: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1, 4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
| NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| UniProt Code: | P13807 |
| NCBI GenInfo Identifier: | 1351366 |
| NCBI Gene ID: | 2997 |
| NCBI Accession: | P13807.2 |
| UniProt Secondary Accession: | P13807,Q9BTT9, |
| UniProt Related Accession: | P13807 |
| Molecular Weight: | 737 |
| NCBI Full Name: | Glycogen |
| NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
| NCBI Official Symbol: | GYS1 |
| NCBI Official Synonym Symbols: | GSY; GYS |
| NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
| UniProt Protein Name: | Glycogen [starch] synthase, muscle |
| Protein Family: | Glycogen [starch] synthase |
| UniProt Gene Name: | GYS1 |
| UniProt Entry Name: | GYS1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GYS1 antibody (CAB2519) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human stomach cancer using GYS1 antibody (CAB2519) at dilution of 1:200 (40x lens). |
 | Immunofluorescence analysis of HeLa cells using GYS1 antibody (CAB2519). Blue: DAPI for nuclear staining. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a
