Cell Biology Antibodies 12

Anti-Guanylin Antibody (CAB9820)

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SKU:
CAB9820
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-Guanylin Antibody
Antibody SKU:CAB9820
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, Mouse small intestine, Rat small intestine
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-115 of human GUCA2A (NP_291031.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VTVQ DGNF SFSL ESVK KLKD LQEP QEPR VGKL RNFA PIPG EPVV PILC SNPN FPEE LKPL CKEP NAQE ILQR LEEI AEDP GTCE ICAY AACT GC
Gene ID:2980
Uniprot:Q02747
Cellular Location:Secreted
Calculated MW:12kDa
Observed MW:12kDa
Synonyms:GUCA2A, GCAP-I, GUCA2, STARA, guanylin
Background:
UniProt Protein Function:GUCA2A: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. Belongs to the guanylin family.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide; Activator

Chromosomal Location of Human Ortholog: 1p35-p34

UniProt Code:Q02747
NCBI GenInfo Identifier:290457645
NCBI Gene ID:2980
NCBI Accession:Q02747.2
UniProt Related Accession:Q02747
Molecular Weight:12,388 Da
NCBI Full Name:Guanylin
NCBI Synonym Full Names:guanylate cyclase activator 2A
NCBI Official Symbol:GUCA2A  
NCBI Official Synonym Symbols:GUCA2; STARA; GCAP-I  
NCBI Protein Information:guanylin
UniProt Protein Name:Guanylin
UniProt Synonym Protein Names:Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Guanylate cyclase-activating protein I; GCAP-I
Protein Family:Guanylin
UniProt Gene Name:GUCA2A  
UniProt Entry Name:GUC2A_HUMAN
Anti-Guanylin Polyclonal Antibody (CAB9820)Western blot analysis of extracts of various cell lines, using GUCA2A antibody (CAB9820) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 5s.
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