Epigenetics & Nuclear Signaling Antibodies 1
Anti-GTF3C6 Antibody (CAB13233)
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- SKU:
- CAB13233
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-GTF3C6 Antibody |
| Antibody SKU: | CAB13233 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-431, K-562, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAA ADER SPED GEDE EEEE QLVL VELS GIID SDFL SKCE NKCK VLGI DTER PILQ VDSC VFAG EYED TLGT CVIF EENV EHAD TEGN NKTV LKYK CHTM KKLS MTRT LLTE KKEG EENI GGVE WLQI KDND FSYR PNMI CNFL HENE DEEV VASA PDKS LELE EEEI QMND SSNL SCEQ EKPM HLEI EDSG PLID IPSE TEGS VFME TQML P |
| Gene ID: | 112495 |
| Uniprot: | Q969F1 |
| Cellular Location: | Nucleus |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
| Synonyms: | GTF3C6, C6orf51, TFIIIC35, bA397G5.3 |
| Background: |
| UniProt Protein Function: | GTF3C6: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. Belongs to the TFIIIC subunit 6 family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 6q21 Cellular Component: nucleoplasm; transcription factor TFIIIC complex Molecular Function:DNA binding; protein binding Biological Process: 5S class rRNA transcription; transcription from RNA polymerase III promoter; transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter |
| UniProt Code: | Q969F1 |
| NCBI GenInfo Identifier: | 19923927 |
| NCBI Gene ID: | 112495 |
| NCBI Accession: | NP_612417.1 |
| UniProt Secondary Accession: | Q969F1,Q5VXN2, |
| UniProt Related Accession: | Q969F1 |
| Molecular Weight: | 24,049 Da |
| NCBI Full Name: | general transcription factor 3C polypeptide 6 |
| NCBI Synonym Full Names: | general transcription factor IIIC subunit 6 |
| NCBI Official Symbol: | GTF3C6 |
| NCBI Official Synonym Symbols: | C6orf51; TFIIIC35; bA397G5.3 |
| NCBI Protein Information: | general transcription factor 3C polypeptide 6 |
| UniProt Protein Name: | General transcription factor 3C polypeptide 6 |
| UniProt Synonym Protein Names: | Transcription factor IIIC 35 kDa subunit; TFIIIC 35 kDa subunit; TFIIIC35; Transcription factor IIIC subunit 6 |
| Protein Family: | General transcription factor 3C polypeptide |
| UniProt Gene Name: | GTF3C6 |
| UniProt Entry Name: | TF3C6_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GTF3C6 antibody (CAB13233) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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