Epigenetics & Nuclear Signaling Antibodies 3
Anti-GTF2H2C Antibody (CAB5239)
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- SKU:
- CAB5239
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-GTF2H2C Antibody |
| Antibody SKU: | CAB5239 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GTF2H2C (NP_001092198.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GTF2H2C (NP_001092198.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDEE PERT KRWE GGYE RTWE ILKE DESG SLKA TIED ILFK AKRK RVFE HHGQ VRLG MMRH LYVV VDGS RTME DQDL KPNR LTCT LKLL EYFV EEYF DQNP ISQI GIIV TKSK RAEK LTEL SGNP RKHI TSLK EAVD MTCH GEPS LYNS LSMA MQTL KHMP GHTS REVL IIFS SLTT CDPS NIYD LIKT LKAA KIRV SVIG LSAE VRVC TVLA RETG GTYH VILD ESHY KELL THHL SPPP ASSS SECS LIRM GFPQ HTIA SLSD QDAK PSFS MAHL DGNT EPGL TLGG YFCP QCRA KYCE |
| Gene ID: | 728340 |
| Uniprot: | Q6P1K8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 44kDa |
| Observed MW: | 44kDa |
| Synonyms: | GTF2H2C, GTF2H2C_2 |
| Background: |
| UniProt Protein Function: | GTF2H2C: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Belongs to the GTF2H2 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 5q13.2 Molecular Function:protein binding |
| UniProt Code: | Q6P1K8 |
| NCBI GenInfo Identifier: | 74737138 |
| NCBI Gene ID: | 730394 |
| NCBI Accession: | Q6P1K8.1 |
| UniProt Secondary Accession: | Q6P1K8,A6NED9, A8K8J6, B2RCU4, B7ZW39, |
| UniProt Related Accession: | Q6P1K8 |
| Molecular Weight: | 44,452 Da |
| NCBI Full Name: | General transcription factor IIH subunit 2-like protein |
| NCBI Synonym Full Names: | GTF2H2 family member C, copy 2 |
| NCBI Official Symbol: | GTF2H2C_2 |
| NCBI Official Synonym Symbols: | GTF2H2D |
| NCBI Protein Information: | general transcription factor IIH subunit 2-like protein |
| UniProt Protein Name: | General transcription factor IIH subunit 2-like protein |
| UniProt Synonym Protein Names: | General transcription factor IIH polypeptide 2-like protein |
| Protein Family: | General transcription factor IIH subunit 2-like protein |
| UniProt Gene Name: | GTF2H2C |
| UniProt Entry Name: | T2H2L_HUMAN |
 | Western blot analysis of extracts of LO2 cells, using GTF2H2C antibody (CAB5239) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded rat brain using GTF2H2C antibody (CAB5239) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat pancreas using GTF2H2C antibody (CAB5239) at dilution of 1:100 (40x lens). |
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