Cell Biology Antibodies 6

Anti-GSTT2 Antibody (CAB15678)

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SKU:
CAB15678
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GSTT2 Antibody
Antibody SKU:CAB15678
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human GSTT2 (NP_000845.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, Mouse heart, Mouse kidney, Mouse liver, Rat liver, Rat kidney, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human GSTT2 (NP_000845.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGLE LFLD LVSQ PSRA VYIF AKKN GIPL ELRT VDLV KGQH KSKE FLQI NSLG KLPT LKDG DFIL TESS AILI YLSC KYQT PDHW YPSD LQAR ARVH EYLG WHAD CIRG TFGI PLWV QVLG PLIG VQVP KEKV ERNR TAMD QALQ WLED KFLG DRPF LAGQ QVTL ADLM ALEE LMQP VALG YELF EGRP RLAA WRGR VEAF LGAE LCQE AHSI ILSI LEQA AKKT LPTP SPEA YQAM LLRI ARIP
Gene ID:2953
Uniprot:P0CG29
Cellular Location:Cytoplasm
Calculated MW:27kDa
Observed MW:27kDa
Synonyms:GSTT2
Background:The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations.
UniProt Protein Function:GST2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. Belongs to the GST superfamily. Theta family.
UniProt Protein Details:

Protein type:EC 2.5.1.18

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: cytoplasm

Molecular Function:glutathione transferase activity

Biological Process: glutathione metabolic process

NCBI Summary:The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015]
UniProt Code:P0CG29
NCBI GenInfo Identifier:300680960
NCBI Gene ID:2953
NCBI Accession:P0CG29.1
UniProt Secondary Accession:P0CG29,O60665, P30712, Q6IPV7, Q9HD76,
UniProt Related Accession:P0CG29
Molecular Weight:27,506 Da
NCBI Full Name:Glutathione S-transferase theta-2
NCBI Synonym Full Names:glutathione S-transferase theta 2 (gene/pseudogene)
NCBI Official Symbol:GSTT2  
NCBI Protein Information:glutathione S-transferase theta-2
UniProt Protein Name:Glutathione S-transferase theta-2
UniProt Synonym Protein Names:GST class-theta-2
Protein Family:Glutathione S-transferase
UniProt Gene Name:GSTT2  
UniProt Entry Name:GST2_HUMAN
Anti-GSTT2 Antibody (CAB15678)Western blot analysis of extracts of various cell lines, using GSTT2 antibody (CAB15678) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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