Name: Anti-GSTO2 Antibody (CAB5774)
Brand: Cell Biology Antibodies 9
SKU: CAB5774
Availability: OutOfStock

Antibody Name:	Anti-GSTO2 Antibody
Antibody SKU:	CAB5774
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 124-243 of human GSTO2 (NP_899062.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse, Rat
Positive Samples:	Rat testis, Mouse pancreas

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 124-243 of human GSTO2 (NP_899062.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	PHLT KECL VALR CGRE CTNL KAAL RQEF SNLE EILE YQNT TFFG GTCI SMID YLLW PWFE RLDV YGIL DCVS HTPA LRLW ISAM KWDP TVCA LLMD KSIF QGFL NLYF QNNP NAFD FGLC
Gene ID:	119391
Uniprot:	Q9H4Y5
Cellular Location:
Calculated MW:	24kDa/25kDa/28kDa
Observed MW:	25kDa

Synonyms:	GSTO2, GSTO 2-2, bA127L20.1, GSTO2-2
Background:	The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	GSTO2: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Transferase; EC 1.20.4.2; EC 1.8.5.1; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 10q25.1 Cellular Component: cytosol Molecular Function:glutathione transferase activity; glutathione dehydrogenase (ascorbate) activity; methylarsonate reductase activity; oxidoreductase activity Biological Process: vitamin metabolic process; xenobiotic metabolic process; L-ascorbic acid metabolic process; water-soluble vitamin metabolic process
NCBI Summary:	The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
UniProt Code:	Q9H4Y5
NCBI GenInfo Identifier:	34922124
NCBI Gene ID:	119391
NCBI Accession:	Q9H4Y5.1
UniProt Secondary Accession:	Q9H4Y5,Q49TW5, Q5GM70, Q5JU15, Q86WP3, A8K771, B4DJW6 E7ESD6,
UniProt Related Accession:	Q9H4Y5
Molecular Weight:	243
NCBI Full Name:	Glutathione S-transferase omega-2
NCBI Synonym Full Names:	glutathione S-transferase omega 2
NCBI Official Symbol:	GSTO2
NCBI Official Synonym Symbols:	GSTO 2-2; bA127L20.1
NCBI Protein Information:	glutathione S-transferase omega-2; GSTO-2; MMA(V) reductase; monomethylarsonic acid reductase; glutathione S-transferase omega 2-2; glutathione-S-transferase-like protein; bA127L20.1 (novel glutathione-S-transferase); glutathione-dependent dehydroascorbate reductase
UniProt Protein Name:	Glutathione S-transferase omega-2
UniProt Synonym Protein Names:	Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase (EC:1.8.5.1); Monomethylarsonic acid reductase (EC:1.20.4.2); MMA(V) reductase
Protein Family:	Glutathione S-transferase
UniProt Gene Name:	GSTO2
UniProt Entry Name:	GSTO2_HUMAN

Western blot analysis of extracts of various cell lines, using GSTO2 antibody (CAB5774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Antibodies

Anti-GSTO2 Antibody (CAB14156)

GSTO2 Antibody (PACO09620)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)