Cell Biology Antibodies 13

Anti-GSTM1 Antibody (CAB17492)

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SKU:
CAB17492
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GSTM1 Antibody
Antibody SKU:CAB17492
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human GSTM1 (NP_666533.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse kidney, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human GSTM1 (NP_666533.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPMI LGYW DIRG LAHA IRLL LEYT DSSY EEKK YTMG DAPD YDRS QWLN EKFK LGLD FPNL PYLI DGAH KITQ SNAI LCYI ARKH NLCG ETEE EKIR VDIL ENQT MDNH MQLG MICY NPEF EKLK PKYL EELP EKLK LYSE FLGK RPWF AGNK GLEK ISAY MKSS RFLP RPVF SKMA VWGN K
Gene ID:2944
Uniprot:P09488
Cellular Location:
Calculated MW:21kDa/25kDa
Observed MW:26kDa
Anti-GSTM1 Antibody (CAB17492)Western blot - GSTM1 Polyclonal Antibody (CAB17492)
Synonyms:GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1, GSTM1
Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
NCBI Summary:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P09488
NCBI GenInfo Identifier:121735
NCBI Gene ID:2944
NCBI Accession:P09488.3
UniProt Related Accession:P09488
Molecular Weight:
NCBI Full Name:Glutathione S-transferase Mu 1
NCBI Synonym Full Names:glutathione S-transferase mu 1
NCBI Official Symbol:GSTM1  
NCBI Official Synonym Symbols:MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b  
NCBI Protein Information:glutathione S-transferase Mu 1
UniProt Protein Name:Glutathione S-transferase Mu 1
UniProt Synonym Protein Names:GST HB subunit 4; GST class-mu 1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4
Protein Family:Glutathione S-transferase
UniProt Gene Name:GSTM1  
UniProt Entry Name:GSTM1_HUMAN
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