| UniProt Protein Function: | GSC: Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Belongs to the paired homeobox family. Bicoid subfamily.Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 14q32.1Biological Process: middle ear morphogenesis; neural crest cell fate specificationDisease: Short Stature, Auditory Canal Atresia, Mandibular Hypoplasia, And Skeletal Abnormalities |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P56915 |
| NCBI GenInfo Identifier: | 61252078 |
| NCBI Gene ID: | 145258 |
| NCBI Accession: | P56915.2 |
| UniProt Secondary Accession: | P56915,Q86YR1 |
| UniProt Related Accession: | P56915 |
| Molecular Weight: | 28,150 Da |
| NCBI Full Name: | Homeobox protein goosecoid |
| NCBI Synonym Full Names: | goosecoid homeobox |
| NCBI Official Symbol: | GSC |
| NCBI Official Synonym Symbols: | SAMS |
| NCBI Protein Information: | homeobox protein goosecoid |
| UniProt Protein Name: | Homeobox protein goosecoid |
| UniProt Synonym Protein Names: | |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | GSC |
| UniProt Entry Name: | GSC_HUMAN |
