Cell Biology Antibodies 9
Anti-GRPEL1 Antibody (CAB4999)
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- SKU:
- CAB4999
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GRPEL1
- Synonyms:
- GrpE
- Synonyms:
- HMGE
- Synonyms:
- mt-GrpE#1
- Synonyms:
- GrpE like 1
- Research Area:
- Cell Biology
Description
| Product Name: | GRPEL1 Rabbit pAb |
| Product Code: | CAB4999 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GRPEL1, GrpE, HMGE, mt-GrpE#1, GrpE like 1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, HL-60, HepG2, Jurkat, Mouse liver, Mouse thymus, Mouse kidney, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAQ CVRL ARRS LPAL ALSL RPSP RLLC TATK QKNS GQNL EEDM GQSE QKAD PPAT EKTL LEEK VKLE EQLK ETVE KYKR ALAD TENL RQRS QKLV EEAK LYGI QAFC KDLL EVAD VLEK ATQC VPKE EIKD DNPH LKNL YEGL VMTE VQIQ KVFT KHGL LKLN PVGA KFDP YEHE ALFH TPVE GKEP GTVA LVSK VGYK LHGR TLRP ALVG VVKE A |
| Gene ID: | 80273 |
| Uniprot: | Q9HAV7 |
| Cellular Location: | Mitochondrion matrix |
| Calculated MW: | 24kDa |
| Observed MW: | 20kDa |
| UniProt Protein Function: | GRPEL1: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Belongs to the GrpE family. |
| UniProt Protein Details: | Protein type:Chaperone; Mitochondrial Chromosomal Location of Human Ortholog: 4p16 Cellular Component: mitochondrion; mitochondrial matrix Molecular Function:protein homodimerization activity; adenyl-nucleotide exchange factor activity; chaperone binding; unfolded protein binding Biological Process: cellular protein metabolic process; protein folding; regulation of catalytic activity; protein targeting to mitochondrion |
| UniProt Code: | Q9HAV7 |
| NCBI GenInfo Identifier: | 18202951 |
| NCBI Gene ID: | 80273 |
| NCBI Accession: | Q9HAV7.2 |
| UniProt Secondary Accession: | Q9HAV7,Q549M6, B2R783, |
| UniProt Related Accession: | Q9HAV7 |
| Molecular Weight: | 24,279 Da |
| NCBI Full Name: | GrpE protein homolog 1, mitochondrial |
| NCBI Synonym Full Names: | GrpE-like 1, mitochondrial (E. coli) |
| NCBI Official Symbol: | GRPEL1 |
| NCBI Official Synonym Symbols: | HMGE |
| NCBI Protein Information: | grpE protein homolog 1, mitochondrial; GrpE-like protein cochaperone; mt-GrpE#1 |
| UniProt Protein Name: | GrpE protein homolog 1, mitochondrial |
| UniProt Synonym Protein Names: | HMGE; Mt-GrpE#1 |
| Protein Family: | GrpE protein |
| UniProt Gene Name: | GRPEL1 |
| UniProt Entry Name: | GRPE1_HUMAN |
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