Cell Biology Antibodies 16
Anti-Grp75 Antibody (CAB11256)
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- SKU:
- CAB11256
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-Grp75 Antibody |
| Antibody SKU: | CAB11256 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Grp75 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, MCF7, Mouse liver, Mouse brain, Mouse kidney, Rat liver, Rat brain, Rat kidney |
| Immunogen: | A synthesized peptide derived from human Grp75 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3313 |
| Uniprot: | P38646 |
| Cellular Location: | Mitochondrion, Nucleus, nucleolus |
| Calculated MW: | 74kDa |
| Observed MW: | 74KDa |
 | Western blot - Grp75 Rabbit mAb (CAB11256) |
| Synonyms: | CRP40, CSA, EVPLS, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74, SAAN, SIDBA4 |
| Background: | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010] |
| UniProt Protein Function: | HSPA9B: Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Belongs to the heat shock protein 70 family. |
| UniProt Protein Details: | Protein type:Nucleolus; Heat shock protein; Chaperone Chromosomal Location of Human Ortholog: 5q31.1 Cellular Component: focal adhesion; mitochondrion; cytoplasm; nucleolus Molecular Function:protein binding; ubiquitin protein ligase binding; unfolded protein binding; ATP binding Biological Process: cellular protein metabolic process; protein folding; protein export from nucleus; protein targeting to mitochondrion; negative regulation of apoptosis |
| NCBI Summary: | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010] |
| UniProt Code: | P38646 |
| NCBI GenInfo Identifier: | 21264428 |
| NCBI Gene ID: | 3313 |
| NCBI Accession: | P38646.2 |
| UniProt Secondary Accession: | P38646,P30036, P31932, Q1HB43, Q53H23, Q6GU03, Q9BWB7 Q9UC56, B2RCM1, |
| UniProt Related Accession: | P38646 |
| Molecular Weight: | 679 |
| NCBI Full Name: | Stress-70 protein, mitochondrial |
| NCBI Synonym Full Names: | heat shock 70kDa protein 9 (mortalin) |
| NCBI Official Symbol: | HSPA9 |
| NCBI Official Synonym Symbols: | CSA; MOT; MOT2; CRP40; GRP75; PBP74; GRP-75; HSPA9B; MTHSP75; HEL-S-124m |
| NCBI Protein Information: | stress-70 protein, mitochondrial; mortalin-2; p66-mortalin; mortalin, perinuclear; heat shock 70kD protein 9B; peptide-binding protein 74; 75 kDa glucose-regulated protein; catecholamine-regulated protein 40; epididymis secretory sperm binding protein Li 124m |
| UniProt Protein Name: | Stress-70 protein, mitochondrial |
| UniProt Synonym Protein Names: | 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74 |
| Protein Family: | Stress-70 protein |
| UniProt Gene Name: | HSPA9 |
| UniProt Entry Name: | GRP75_HUMAN |
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