Cell Biology Antibodies 2

Anti-GRIPAP1 Antibody (CAB12044)

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SKU:
CAB12044
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GRIPAP1 Antibody
Antibody SKU:CAB12044
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 642-841 of human GRIPAP1 (NP_064522.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-87MG, HeLa, Jurkat, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 642-841 of human GRIPAP1 (NP_064522.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RSGL EELV LSEM NSPS RTQT GDSS SISS FSYR EILR EKES SAVP ARSL SSSP QAQP PRPA ELSD EEVA ELFQ RLAE TQQE KWML EEKV KHLE VSSA SMAE DLCR KSAI IETY VMDS RIDV SVAA GHTD RSGL GSVL RDLV KPGD ENLR EMNK KLQN MLEE QLTK NMHL HKDM EVLS QEIV RLSK ECVG PPDP DLEP GETS
Gene ID:56850
Uniprot:Q4V328
Cellular Location:Early endosome
Calculated MW:68kDa/71kDa/92kDa/95kDa
Observed MW:110kDa
Synonyms:GRIPAP1, GRASP-1
Background:This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function.
UniProt Protein Function:GRIPAP1: a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.[provided by RefSeq, Nov 2009]
UniProt Protein Details:

Protein type:GEF; GEF, Ras

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: cytosol; intracellular membrane-bound organelle; nucleoplasm

Molecular Function:protein binding

NCBI Summary:This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013]
UniProt Code:Q4V328
NCBI GenInfo Identifier:74753569
NCBI Gene ID:56850
NCBI Accession:Q4V328.1
UniProt Secondary Accession:Q4V328,Q3MJ75, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8 Q9NQ43, Q9ULQ3, A6NL78,
UniProt Related Accession:Q4V328
Molecular Weight:96kDa
NCBI Full Name:GRIP1-associated protein 1
NCBI Synonym Full Names:GRIP1 associated protein 1
NCBI Official Symbol:GRIPAP1  
NCBI Official Synonym Symbols:GRASP-1  
NCBI Protein Information:GRIP1-associated protein 1
UniProt Protein Name:GRIP1-associated protein 1
Protein Family:GRIP1-associated protein
UniProt Gene Name:GRIPAP1  
Anti-GRIPAP1 Antibody (CAB12044)Western blot analysis of extracts of various cell lines, using GRIPAP1 antibody (CAB12044) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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