Signal Transduction Antibodies 3

Anti-GRID1 Antibody (CAB8011)

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SKU:
CAB8011
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction

Description

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Antibody Name:GRID1 Rabbit Polyclonal Antibody
Antibody SKU:CAB8011
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 880-1009 of human GRID1 (NP_060021.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat spinal cord
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 880-1009 of human GRID1 (NP_060021.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MNSL MDED IAHK QISP ASIE LSAL EMGG LAPT QTLE PTRE YQNT QLSV STFL PEQS SHGT SRTL SSGP SSNL PLPL SSSA TMPS MQCK HRSP NGGL FRQS PVKT PIPM SFQP VPGG VLPE ALDT SHGT SI
Gene ID:2894
Uniprot:Q9ULK0
Cellular Location:Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Calculated MW:63kDa/112kDa
Observed MW:100kDa
Synonyms:GRID1, GluD1, delta-1
Background:This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.
UniProt Protein Function:GluR-delta1: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID1 subfamily.
UniProt Protein Details:

Protein type:Membrane protein, integral; Receptor, misc.; Channel, calcium; Membrane protein, multi-pass; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 10q22

Biological Process: social behavior

NCBI Summary:This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
UniProt Code:Q9ULK0
NCBI GenInfo Identifier:38372397
NCBI Gene ID:2894
NCBI Accession:Q9ULK0.2
UniProt Secondary Accession:Q9ULK0,Q8IXT3, B3KXD5, B7Z7L0,
UniProt Related Accession:Q9ULK0
Molecular Weight:63,658 Da
NCBI Full Name:Glutamate receptor ionotropic, delta-1
NCBI Synonym Full Names:glutamate ionotropic receptor delta type subunit 1
NCBI Official Symbol:GRID1  
NCBI Official Synonym Symbols:GluD1  
NCBI Protein Information:glutamate receptor ionotropic, delta-1
UniProt Protein Name:Glutamate receptor ionotropic, delta-1
Protein Family:Glutamate receptor ionotropic
UniProt Gene Name:GRID1  
UniProt Entry Name:GRID1_HUMAN
Anti-GRID1 Polyclonal Antibody (CAB8011)Western blot analysis of extracts of various cell lines, using GRID1 antibody (CAB8011) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-GRID1 Polyclonal Antibody (CAB8011)Immunofluorescence analysis of L929 cells using GRID1 Rabbit pAb (CAB8011) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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