Anti-GRASP65 Antibody (CAB2316)
- SKU:
- CAB2316
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GOLPH5
- Synonyms:
- GRASP65
- Synonyms:
- P65
- Research Area:
- Cell Biology
Description
| Product Name: | GRASP65 Rabbit mAb |
| Product Code: | CAB2316 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GOLPH5, GRASP65, P65 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GRASP65 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human GRASP65 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64689 |
| Uniprot: | Q9BQQ3 |
| Calculated MW: | 65kDa |
| Observed MW: | 70kDa |
| UniProt Protein Function: | GRASP65: Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes. Belongs to the GORASP family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 3p22-p21.33 Cellular Component: Golgi membrane; Golgi apparatus Biological Process: protein transport; negative regulation of dendrite morphogenesis; mitotic cell cycle; Golgi organization and biogenesis |
| NCBI Summary: | The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9BQQ3 |
| NCBI GenInfo Identifier: | 51316077 |
| NCBI Gene ID: | 64689 |
| NCBI Accession: | Q9BQQ3.3 |
| UniProt Related Accession: | Q9BQQ3 |
| Molecular Weight: | |
| NCBI Full Name: | Golgi reassembly-stacking protein 1 |
| NCBI Synonym Full Names: | golgi reassembly stacking protein 1 |
| NCBI Official Symbol: | GORASP1 |
| NCBI Official Synonym Symbols: | P65; GOLPH5; GRASP65 |
| NCBI Protein Information: | Golgi reassembly-stacking protein 1 |
| UniProt Protein Name: | Golgi reassembly-stacking protein 1 |
| UniProt Synonym Protein Names: | Golgi peripheral membrane protein p65; Golgi phosphoprotein 5; GOLPH5; Golgi reassembly-stacking protein of 65 kDa; GRASP65 |
| UniProt Gene Name: | GORASP1 |
| UniProt Entry Name: | GORS1_HUMAN |
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