Anti-GPX5 Antibody (CAB1075)
- SKU:
- CAB1075
Description
| Product Name: | GPX5 Rabbit pAb |
| Product Code: | CAB1075 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GPX5, HEL-S-75p |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GPX5 (NP_003987.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GPX5 (NP_003987.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTTQ LRVV HLLP LLLA CFVQ TSPK QEKM KMDC HKDE KGTI YDYE AIAL NKNE YVSF KQYV GKHI LFVN VATY CGLT AQYP GMSV QGED LYLV SSFL RKGM |
| Gene ID: | 2880 |
| Uniprot: | O75715 |
| Cellular Location: | Secreted |
| Calculated MW: | 11kDa/25kDa |
| Observed MW: | 25kDa |
| UniProt Protein Function: | GPX5: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Belongs to the glutathione peroxidase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.11.1.9; Secreted, signal peptide; Other Amino Acids Metabolism - glutathione; Oxidoreductase; Lipid Metabolism - arachidonic acid; SecretedChromosomal Location of Human Ortholog: 6p22.1Cellular Component: extracellular spaceMolecular Function: glutathione peroxidase activityBiological Process: response to oxidative stress; lipid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016] |
| UniProt Code: | O75715 |
| NCBI GenInfo Identifier: | 6016164 |
| NCBI Gene ID: | 2880 |
| NCBI Accession: | O75715.1 |
| UniProt Secondary Accession: | O75715,P21765 |
| UniProt Related Accession: | O75715 |
| Molecular Weight: | |
| NCBI Full Name: | Epididymal secretory glutathione peroxidase |
| NCBI Synonym Full Names: | glutathione peroxidase 5 |
| NCBI Official Symbol: | GPX5 |
| NCBI Official Synonym Symbols: | EGLP; GPx-5; GSHPx-5; HEL-S-75p |
| NCBI Protein Information: | epididymal secretory glutathione peroxidase |
| UniProt Protein Name: | Epididymal secretory glutathione peroxidase |
| UniProt Synonym Protein Names: | Epididymis-specific glutathione peroxidase-like protein; EGLP; Glutathione peroxidase 5; GPx-5; GSHPx-5 |
| Protein Family: | Probable glutathione peroxidase |
| UniProt Gene Name: | GPX5 |
| UniProt Entry Name: | GPX5_HUMAN |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Polyclonal Antibody |
Reactivity: |
Human |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
Synonyms: |
GPX5 |
Synonyms: |
HEL-S-75p |
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