Cell Biology Antibodies 5
Anti-GPR87 Antibody (CAB15162)
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- SKU:
- CAB15162
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GPR87 Antibody |
| Antibody SKU: | CAB15162 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR87 (NP_076404.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | DU145 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR87 (NP_076404.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HNQS IRVV VAVF FTCF LPYH LCRI PFTF SHLD RLLD ESAQ KILY YCKE ITLF LSAC NVCL DPII YFFM CRSF SRRL FKKS NIRT RSES IRSL QSVR RSEV R |
| Gene ID: | 53836 |
| Uniprot: | Q9BY21 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 41kDa |
| Synonyms: | GPR87, FKSG78, GPR95, KPG_002 |
| Background: | This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). |
| UniProt Protein Function: | GPR87: Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 3q24 Cellular Component: integral to plasma membrane Molecular Function:purinergic nucleotide receptor activity, G-protein coupled Biological Process: negative regulation of adenylate cyclase activity |
| NCBI Summary: | This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011] |
| UniProt Code: | Q9BY21 |
| NCBI GenInfo Identifier: | 37537842 |
| NCBI Gene ID: | 53836 |
| NCBI Accession: | Q9BY21.1 |
| UniProt Secondary Accession: | Q9BY21,Q5KU35, Q96JZ8, Q9BXC2, |
| UniProt Related Accession: | Q9BY21 |
| Molecular Weight: | |
| NCBI Full Name: | G-protein coupled receptor 87 |
| NCBI Synonym Full Names: | G protein-coupled receptor 87 |
| NCBI Official Symbol: | GPR87 |
| NCBI Official Synonym Symbols: | GPR95; FKSG78; KPG_002 |
| NCBI Protein Information: | G-protein coupled receptor 87 |
| UniProt Protein Name: | G-protein coupled receptor 87 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 95 |
| Protein Family: | G-protein coupled receptor |
| UniProt Gene Name: | GPR87 |
| UniProt Entry Name: | GPR87_HUMAN |
 | Western blot analysis of extracts of DU145 cells, using GPR87 antibody (CAB15162) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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