Cell Biology Antibodies 5

Anti-GPR87 Antibody (CAB15162)

(No reviews yet) Write a Review
SKU:
CAB15162
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-GPR87 Antibody
Antibody SKU:CAB15162
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR87 (NP_076404.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:DU145
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR87 (NP_076404.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HNQS IRVV VAVF FTCF LPYH LCRI PFTF SHLD RLLD ESAQ KILY YCKE ITLF LSAC NVCL DPII YFFM CRSF SRRL FKKS NIRT RSES IRSL QSVR RSEV R
Gene ID:53836
Uniprot:Q9BY21
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:41kDa
Observed MW:41kDa
Synonyms:GPR87, FKSG78, GPR95, KPG_002
Background:This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589).
UniProt Protein Function:GPR87: Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: integral to plasma membrane

Molecular Function:purinergic nucleotide receptor activity, G-protein coupled

Biological Process: negative regulation of adenylate cyclase activity

NCBI Summary:This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]
UniProt Code:Q9BY21
NCBI GenInfo Identifier:37537842
NCBI Gene ID:53836
NCBI Accession:Q9BY21.1
UniProt Secondary Accession:Q9BY21,Q5KU35, Q96JZ8, Q9BXC2,
UniProt Related Accession:Q9BY21
Molecular Weight:
NCBI Full Name:G-protein coupled receptor 87
NCBI Synonym Full Names:G protein-coupled receptor 87
NCBI Official Symbol:GPR87  
NCBI Official Synonym Symbols:GPR95; FKSG78; KPG_002  
NCBI Protein Information:G-protein coupled receptor 87
UniProt Protein Name:G-protein coupled receptor 87
UniProt Synonym Protein Names:G-protein coupled receptor 95
Protein Family:G-protein coupled receptor
UniProt Gene Name:GPR87  
UniProt Entry Name:GPR87_HUMAN
Anti-GPR87 Antibody (CAB15162)Western blot analysis of extracts of DU145 cells, using GPR87 antibody (CAB15162) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products