Cell Biology Antibodies 5
Anti-GPR6 Antibody (CAB14738)
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- SKU:
- CAB14738
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GPR6 Antibody |
| Antibody SKU: | CAB14738 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_005275.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-251MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_005275.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WRHA HQIA LQQH CLAP PHLA ATRK GVGT LAVV LGTF GASW LPFA IYCV VGSH EDPA VYTY ATLL PATY NSMI NPII YAFR NQEI QRAL WLLL CGCF QSKV PFRS RSPS EV |
| Gene ID: | 2830 |
| Uniprot: | P46095 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 37kDa/39kDa |
| Observed MW: | 38kDa |
| Synonyms: | GPR6 |
| Background: |
| UniProt Protein Function: | GPR6: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 6q21 Cellular Component: integral to plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration |
| UniProt Code: | P46095 |
| NCBI GenInfo Identifier: | 1170009 |
| NCBI Gene ID: | 2830 |
| NCBI Accession: | P46095.1 |
| UniProt Secondary Accession: | P46095,Q17RJ7, Q5SYL0, B4DHS9, J3KQR3, |
| UniProt Related Accession: | P46095 |
| Molecular Weight: | 362 |
| NCBI Full Name: | G-protein coupled receptor 6 |
| NCBI Synonym Full Names: | G protein-coupled receptor 6 |
| NCBI Official Symbol: | GPR6 |
| NCBI Protein Information: | G-protein coupled receptor 6; sphingosine 1-phosphate receptor GPR6 |
| UniProt Protein Name: | G-protein coupled receptor 6 |
| UniProt Synonym Protein Names: | Sphingosine 1-phosphate receptor GPR6 |
| Protein Family: | G-protein coupled receptor |
| UniProt Gene Name: | GPR6 |
| UniProt Entry Name: | GPR6_HUMAN |
 | Western blot analysis of extracts of U-251MG cells, using GPR6 antibody (CAB14738) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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