Cell Biology Antibodies 6
Anti-GPR45 Antibody (CAB15790)
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- SKU:
- CAB15790
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GPR45 Antibody |
| Antibody SKU: | CAB15790 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR45 (NP_009158.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | SH-SY5Y |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human GPR45 (NP_009158.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VIIA VSWV LSFC IAGP SLTG WTLV EVPA RAPQ CVLG YTEL PADR AYVV TLVV AVFF APFG VMLC AYMC ILNT VRKN AVRV HNQS DSLD LRQL TRAG LRRL Q |
| Gene ID: | 11250 |
| Uniprot: | Q9Y5Y3 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 45kDa |
| Synonyms: | GPR45, PSP24, PSP24(ALPHA), PSP24A |
| Background: | This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. |
| UniProt Protein Function: | GPR45: Orphan receptor. May play a role in brain function. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 2q11.1-q12 Cellular Component: plasma membrane Molecular Function:G-protein coupled receptor activity |
| NCBI Summary: | This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5Y3 |
| NCBI GenInfo Identifier: | 82654940 |
| NCBI Gene ID: | 11250 |
| NCBI Accession: | Q9Y5Y3.2 |
| UniProt Secondary Accession: | Q9Y5Y3,Q6NWS4, Q6NXU6, |
| UniProt Related Accession: | Q9Y5Y3 |
| Molecular Weight: | 41,967 Da |
| NCBI Full Name: | Probable G-protein coupled receptor 45 |
| NCBI Synonym Full Names: | G protein-coupled receptor 45 |
| NCBI Official Symbol: | GPR45 |
| NCBI Official Synonym Symbols: | PSP24; PSP24A; PSP24(ALPHA) |
| NCBI Protein Information: | probable G-protein coupled receptor 45 |
| UniProt Protein Name: | Probable G-protein coupled receptor 45 |
| UniProt Synonym Protein Names: | PSP24-1; PSP24-alpha |
| Protein Family: | Probable G-protein coupled receptor |
| UniProt Gene Name: | GPR45 |
| UniProt Entry Name: | GPR45_HUMAN |
 | Western blot analysis of extracts of SH-SY5Y cells, using GPR45 antibody (CAB15790) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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