Cell Biology Antibodies 7

Anti-GPR37 Antibody (CAB16724)

(No reviews yet) Write a Review
SKU:
CAB16724
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-GPR37 Antibody
Antibody SKU:CAB16724
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human GPR37 (NP_005293.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:U-87MG, U-251MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human GPR37 (NP_005293.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LGES CAPT VIQR RGRD AWGP GNSA RDVL RARA PREE QGAA FLAG PSWD LPAA PGRD PAAG RGAE ASAA GPPG PPTR PPGP WRWK GARG QEPS ETLG RGNP TALQ LFLQ ISEE EEKG PRGA GISG RSQE QSVK TVPG ASDL F
Gene ID:2861
Uniprot:O15354
Cellular Location:
Calculated MW:67kDa
Observed MW:67kDa
Synonyms:GPR37, EDNRBL, PAELR, hET(B)R-LP
Background:This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.
UniProt Protein Function:GPR37: Orphan receptor. May have a unique functional role in the central nervous system. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; ubiquitin ligase complex; receptor complex

Molecular Function:G-protein coupled receptor activity; protein binding; ubiquitin protein ligase binding; heat shock protein binding; peptide receptor activity, G-protein coupled; Hsp70 protein binding; peptide binding

Biological Process: positive regulation of dopamine metabolic process; G-protein coupled receptor protein signaling pathway; positive regulation of MAPKKK cascade; dopamine biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; locomotion during locomotory behavior

NCBI Summary:This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]
UniProt Code:O15354
NCBI GenInfo Identifier:4885323
NCBI Gene ID:2861
NCBI Accession:NP_005293.1
UniProt Secondary Accession:O15354,O00348, O14768, Q8TD39,
UniProt Related Accession:O15354
Molecular Weight:67,114 Da
NCBI Full Name:probable G-protein coupled receptor 37
NCBI Synonym Full Names:G protein-coupled receptor 37 (endothelin receptor type B-like)
NCBI Official Symbol:GPR37  
NCBI Official Synonym Symbols:PAELR; EDNRBL; hET(B)R-LP  
NCBI Protein Information:probable G-protein coupled receptor 37; ETBR-LP-1; endothelin B receptor-like protein 1; Parkin-associated endothelin receptor-like receptor
UniProt Protein Name:Probable G-protein coupled receptor 37
UniProt Synonym Protein Names:Endothelin B receptor-like protein 1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor
Protein Family:Prosaposin receptor
UniProt Gene Name:GPR37  
UniProt Entry Name:GPR37_HUMAN
Anti-GPR37 Antibody (CAB16724)Western blot analysis of extracts of various cell lines, using GPR37 antibody (CAB16724) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products

Human GPR37 Recombinant Protein (RPES4956)

Human GPR37 Recombinant Protein (RPES4956)

system_update_altDatasheetHuman GPR37 Recombinant Protein GPR37 (cathepsin Z) is an orphan receptor which belongs to the G-protein coupled receptor 1 family. G protein coupled receptors is a larg