Cell Biology Antibodies 14
Anti-GPR35 Antibody (CAB17953)
- SKU:
- CAB17953
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-GPR35 Antibody |
Antibody SKU: | CAB17953 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GPR35 (NP_005292.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse |
Positive Samples: | Mouse brain, mouse stomach, mouse liver |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GPR35 (NP_005292.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | QQWT ETRI YMTN LAVA DLCL LCTL PFVL HSLR DTSD TPLC QLSQ GIYL TNRY MSIS LVTA IAVD RYVA VRHP LRAR GLRS PRQA AAVC AVLW VLVI GSLV A |
Gene ID: | 2859 |
Uniprot: | Q9HC97 |
Cellular Location: | |
Calculated MW: | 34kDa |
Observed MW: | 34kDa |
Synonyms: | GPR35 |
Background: |
UniProt Protein Function: | GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: integral to plasma membrane Molecular Function:C-X-C chemokine receptor activity; G-protein coupled receptor activity Biological Process: elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; positive regulation of Rho protein signal transduction |
UniProt Code: | Q9HC97 |
NCBI GenInfo Identifier: | 68068087 |
NCBI Gene ID: | 2859 |
NCBI Accession: | Q9HC97.4 |
UniProt Secondary Accession: | Q9HC97,O43495, Q17R58, Q4VBN5, Q4ZFV2, Q6FHI8, Q86UH4 J3KR30, |
UniProt Related Accession: | Q9HC97 |
Molecular Weight: | 37,452 Da |
NCBI Full Name: | G-protein coupled receptor 35 |
NCBI Synonym Full Names: | G protein-coupled receptor 35 |
NCBI Official Symbol: | GPR35 |
NCBI Protein Information: | G-protein coupled receptor 35 |
UniProt Protein Name: | G-protein coupled receptor 35 |
UniProt Synonym Protein Names: | Kynurenic acid receptor; KYNA receptor |
Protein Family: | G-protein coupled receptor |
UniProt Gene Name: | GPR35 |