Cell Biology Antibodies 14
Anti-GPR35 Antibody (CAB17953)
- SKU:
 - CAB17953
 - Product Type:
 - Antibody
 - Reactivity:
 - Mouse
 - Host Species:
 - Rabbit
 - Isotype:
 - IgG
 - Research Area:
 - Cell Biology
 
Description
| Antibody Name: | Anti-GPR35 Antibody | 
| Antibody SKU: | CAB17953 | 
| Antibody Size: | 20uL, 50uL, 100uL | 
| Application: | WB | 
| Reactivity: | Mouse | 
| Host Species: | Rabbit | 
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GPR35 (NP_005292.2). | 
| Application: | WB | 
| Recommended Dilution: | WB 1:500 - 1:2000 | 
| Reactivity: | Mouse | 
| Positive Samples: | Mouse brain, mouse stomach, mouse liver | 
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GPR35 (NP_005292.2). | 
| Purification Method: | Affinity purification | 
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Isotype: | IgG | 
| Sequence: | QQWT ETRI YMTN LAVA DLCL LCTL PFVL HSLR DTSD TPLC QLSQ GIYL TNRY MSIS LVTA IAVD RYVA VRHP LRAR GLRS PRQA AAVC AVLW VLVI GSLV A | 
| Gene ID: | 2859 | 
| Uniprot: | Q9HC97 | 
| Cellular Location: | |
| Calculated MW: | 34kDa | 
| Observed MW: | 34kDa | 
| Synonyms: | GPR35 | 
| Background: | 
| UniProt Protein Function: | GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family. | 
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: integral to plasma membrane Molecular Function:C-X-C chemokine receptor activity; G-protein coupled receptor activity Biological Process: elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; positive regulation of Rho protein signal transduction  | 
| UniProt Code: | Q9HC97 | 
| NCBI GenInfo Identifier: | 68068087 | 
| NCBI Gene ID: | 2859 | 
| NCBI Accession: | Q9HC97.4 | 
| UniProt Secondary Accession: | Q9HC97,O43495, Q17R58, Q4VBN5, Q4ZFV2, Q6FHI8, Q86UH4 J3KR30, | 
| UniProt Related Accession: | Q9HC97 | 
| Molecular Weight: | 37,452 Da | 
| NCBI Full Name: | G-protein coupled receptor 35 | 
| NCBI Synonym Full Names: | G protein-coupled receptor 35 | 
| NCBI Official Symbol: | GPR35 | 
| NCBI Protein Information: | G-protein coupled receptor 35 | 
| UniProt Protein Name: | G-protein coupled receptor 35 | 
| UniProt Synonym Protein Names: | Kynurenic acid receptor; KYNA receptor | 
| Protein Family: | G-protein coupled receptor | 
| UniProt Gene Name: | GPR35 | 
            