Cell Biology Antibodies 5

Anti-GPR182 Antibody (CAB14854)

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SKU:
CAB14854
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GPR182 Antibody
Antibody SKU:CAB14854
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR182 (NP_009195.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:LO2, 293T, mouse liver
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GPR182 (NP_009195.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QPKS RRHC LLLC AYVA VFVM CWLP YHVT LLLL TLHG THIS LHCH LVHL LYFF YDVI DCFS MLHC VINP ILYN FLSP HFRG RLLN AVVH YLPK DQTK AGTC A
Gene ID:11318
Uniprot:O15218
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:45kDa
Observed MW:45kDa
Synonyms:GPR182, 7TMR, ADMR, AM-R, AMR, G10D, gamrh, hrhAMR
Background:Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin.
UniProt Protein Function:GPR182: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; transmembrane receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction

NCBI Summary:Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008]
UniProt Code:O15218
NCBI GenInfo Identifier:10719861
NCBI Gene ID:11318
NCBI Accession:O15218.1
UniProt Related Accession:O15218
Molecular Weight:45,323 Da
NCBI Full Name:G-protein coupled receptor 182
NCBI Synonym Full Names:G protein-coupled receptor 182
NCBI Official Symbol:GPR182  
NCBI Official Synonym Symbols:AMR; 7TMR; ADMR; AM-R; G10D; gamrh; hrhAMR  
NCBI Protein Information:G-protein coupled receptor 182; adrenomedullin receptor
UniProt Protein Name:G-protein coupled receptor 182
Protein Family:G-protein coupled receptor
UniProt Gene Name:GPR182  
UniProt Entry Name:GP182_HUMAN
Anti-GPR182 Antibody (CAB14854)Western blot analysis of extracts of various cell lines, using GPR182 antibody (CAB14854) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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