Cell Biology Antibodies 2
Anti-GPHA2 Antibody (CAB10601)
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- SKU:
- CAB10601
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GPHA2 Antibody |
| Antibody SKU: | CAB10601 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-129 of human GPHA2 (NP_570125.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Rat |
| Positive Samples: | Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-129 of human GPHA2 (NP_570125.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QEAV IPGC HLHP FNVT VRSD RQGT CQGS HVAQ ACVG HCES SAFP SRYS VLVA SGYR HNIT SVSQ CCTI SGLK KVKV QLQC VGSR REEL EIFT ARAC QCDM CRLS RY |
| Gene ID: | 170589 |
| Uniprot: | Q96T91 |
| Cellular Location: | Secreted |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | GPHA2, A2, GPA2, ZSIG51 |
| Background: |
| UniProt Protein Function: | GPHA2: Stimulates the thyroid. Binds and activates THSR, leads to increased cAMP production. Belongs to the glycoprotein hormones subunit alpha family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: extracellular region Molecular Function:protein heterodimerization activity; thyrotropin-releasing hormone receptor binding Biological Process: cell surface receptor linked signal transduction; positive regulation of cAMP biosynthetic process |
| NCBI Summary: | GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96T91 |
| NCBI GenInfo Identifier: | 48474600 |
| NCBI Gene ID: | 170589 |
| NCBI Accession: | Q96T91.1 |
| UniProt Secondary Accession: | Q96T91,Q52LE2, |
| UniProt Related Accession: | Q96T91 |
| Molecular Weight: | 14kDa |
| NCBI Full Name: | Glycoprotein hormone alpha-2 |
| NCBI Synonym Full Names: | glycoprotein hormone alpha 2 |
| NCBI Official Symbol: | GPHA2 |
| NCBI Official Synonym Symbols: | A2; GPA2; ZSIG51 |
| NCBI Protein Information: | glycoprotein hormone alpha-2 |
| UniProt Protein Name: | Glycoprotein hormone alpha-2 |
| UniProt Synonym Protein Names: | Putative secreted protein Zsig51; Thyrostimulin subunit alpha |
| Protein Family: | Glycoprotein hormone |
| UniProt Gene Name: | GPHA2 |
 | Western blot analysis of extracts of rat brain, using GPHA2 antibody (CAB10601) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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