Description
| Product Name: | GPA33 Rabbit mAb |
| Product Code: | CAB3608 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | A33 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GPA33 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HCT116, HT-29, A-549, Mouse stomach, Rat large intestine |
| Immunogen: | A synthesized peptide derived from human GPA33 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10223 |
| Uniprot: | Q99795 |
| Calculated MW: | 50kDa |
| Observed MW: | 39kDa |
| UniProt Protein Function: | GPA33: May play a role in cell-cell recognition and signaling. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1q24.1 Cellular Component: integral to plasma membrane Molecular Function:receptor activity |
| NCBI Summary: | The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99795 |
| NCBI GenInfo Identifier: | 5031561 |
| NCBI Gene ID: | 10223 |
| NCBI Accession: | NP_005805.1 |
| UniProt Secondary Accession: | Q99795,Q5VZP6, |
| UniProt Related Accession: | Q99795 |
| Molecular Weight: | 35,632 Da |
| NCBI Full Name: | cell surface A33 antigen |
| NCBI Synonym Full Names: | glycoprotein A33 |
| NCBI Official Symbol: | GPA33 |
| NCBI Official Synonym Symbols: | A33 |
| NCBI Protein Information: | cell surface A33 antigen |
| UniProt Protein Name: | Cell surface A33 antigen |
| UniProt Synonym Protein Names: | Glycoprotein A33 |
| UniProt Gene Name: | GPA33 |
| UniProt Entry Name: | GPA33_HUMAN |