Cell Biology Antibodies 3
Anti-GP2 Antibody (CAB12438)
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- SKU:
- CAB12438
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GP2 Antibody |
| Antibody SKU: | CAB12438 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse kidney, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-387 of human GP2 (NP_001007243.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CSSI LQTE ERNW VSVT SPVQ ASAC RNIL ERNQ THAI YKNT LSLV NDFI IRDT ILNI NFQC AYPL DMKV SLQA ALQP IVSS LNVS VDGN GEFI VRMA LFQD QNYT NPYE GDAV ELSV ESVL YVGA ILEQ GDTS RFNL VLRN CYAT PTED KADL VKYF IIRN SCSN QRDS TIHV EENG QSSE SRFS VQMF MFAG HYDL VFLH CEIH LCDS LNEQ CQPS CSRS QVRS EVPA IDLA RVLD LGPI TRRG AQSP GVMN GTPS TAGF LVAW PMVL LTVL LAWL F |
| Gene ID: | 2813 |
| Uniprot: | P55259 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Secreted |
| Calculated MW: | 43kDa/59kDa |
| Observed MW: | 59kDa |
| Synonyms: | GP2, ZAP75 |
| Background: | This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. |
| NCBI Summary: | This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | P55259 |
| NCBI GenInfo Identifier: | 215274153 |
| NCBI Gene ID: | 2813 |
| NCBI Accession: | P55259.3 |
| UniProt Secondary Accession: | P55259,Q13338, Q9UIF1, A6NFM9, A6NJA8, |
| UniProt Related Accession: | P55259 |
| Molecular Weight: | Calculated MW: 43kDa/59kDaObserved MW: 59kDa |
| NCBI Full Name: | Pancreatic secretory granule membrane major glycoprotein GP2 |
| NCBI Synonym Full Names: | glycoprotein 2 |
| NCBI Official Symbol: | GP2 |
| NCBI Official Synonym Symbols: | ZAP75 |
| NCBI Protein Information: | pancreatic secretory granule membrane major glycoprotein GP2 |
| UniProt Protein Name: | Pancreatic secretory granule membrane major glycoprotein GP2 |
| UniProt Synonym Protein Names: | Pancreatic zymogen granule membrane protein GP-2; ZAP75 |
| Protein Family: | Polygalacturonase |
| UniProt Gene Name: | GP2 |
 | Western blot analysis of extracts of various cell lines, using GP2 antibody (CAB12438) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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