Cell Biology Antibodies 4

Anti-GNGT2 Antibody (CAB13992)

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SKU:
CAB13992
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GNGT2 Antibody
Antibody SKU:CAB13992
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human GNGT2 (NP_113686.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human GNGT2 (NP_113686.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAQD LSEK DLLK MEVE QLKK EVKN TRIP ISKA GKEI KEYV EAQA GNDP FLKG IPED KNPF KEKG GCLI S
Gene ID:2793
Uniprot:O14610
Cellular Location:Cell membrane, Cytoplasmic side, Lipid-anchor
Calculated MW:7kDa
Observed MW:13kDa
Synonyms:GNGT2, G-GAMMA-8, G-GAMMA-C, GNG8, GNG9, GNGT8
Background:Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.
UniProt Protein Function:G-gamma t2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.
UniProt Protein Details:

Protein type:G protein; G protein, heterotrimeric; G protein, heterotrimeric gamma

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: heterotrimeric G-protein complex; plasma membrane

Molecular Function:GTPase activity

NCBI Summary:Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2010]
UniProt Code:O14610
NCBI GenInfo Identifier:3023844
NCBI Gene ID:2793
NCBI Accession:O14610.1
UniProt Secondary Accession:O14610,B2R746, D3DTW5,
UniProt Related Accession:O14610
Molecular Weight:8kDa
NCBI Full Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
NCBI Synonym Full Names:G protein subunit gamma transducin 2
NCBI Official Symbol:GNGT2  
NCBI Official Synonym Symbols:GNG8; GNG9; GNGT8; G-GAMMA-8; G-GAMMA-C  
NCBI Protein Information:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
UniProt Protein Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
UniProt Synonym Protein Names:G gamma-C; G-gamma-8; G-gamma-9; Guanine nucleotide binding protein gamma transducing activity polypeptide 2
UniProt Gene Name:GNGT2  
Anti-GNGT2 Antibody (CAB13992)Western blot analysis of extracts of mouse spleen, using GNGT2 antibody (CAB13992) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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