Cell Biology Antibodies 1

Anti-GNG7 Antibody (CAB10009)

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SKU:
CAB10009
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GNG7 Antibody
Antibody SKU:CAB10009
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_443079.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_443079.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSAT NNIA QARK LVEQ LRIE AGIE RIKV SKAA SDLM SYCE QHAR NDPL LVGV PASE NPFK DKKP CIIL
Gene ID:2788
Uniprot:O60262
Cellular Location:Cell membrane, Cytoplasmic side, Lipid-anchor
Calculated MW:7kDa
Observed MW:12kDa
Synonyms:GNG7
Background:
UniProt Protein Function:G-gamma 7: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. Belongs to the G protein gamma family.
UniProt Protein Details:

Protein type:G protein, heterotrimeric gamma; G protein; G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: plasma membrane; heterotrimeric G-protein complex

Molecular Function:signal transducer activity

Biological Process: regulation of adenylate cyclase activity; G-protein coupled receptor protein signaling pathway; synaptic transmission; behavioral fear response; receptor guanylyl cyclase signaling pathway; energy reserve metabolic process; locomotory behavior; regulation of G-protein coupled receptor protein signaling pathway

UniProt Code:O60262
NCBI GenInfo Identifier:32698769
NCBI Gene ID:2788
NCBI Accession:NP_443079.1
UniProt Secondary Accession:O60262,B2R496,
UniProt Related Accession:O60262
Molecular Weight:7,522 Da
NCBI Full Name:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
NCBI Synonym Full Names:guanine nucleotide binding protein (G protein), gamma 7
NCBI Official Symbol:GNG7  
NCBI Protein Information:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
UniProt Protein Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
UniProt Gene Name:GNG7  
UniProt Entry Name:GBG7_HUMAN
Anti-GNG7 Antibody (CAB10009)Western blot analysis of extracts of various cell lines, using GNG7 antibody (CAB10009) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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