Cell Biology Antibodies 1
Anti-GNG7 Antibody (CAB10009)
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- SKU:
- CAB10009
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GNG7 Antibody |
| Antibody SKU: | CAB10009 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_443079.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_443079.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSAT NNIA QARK LVEQ LRIE AGIE RIKV SKAA SDLM SYCE QHAR NDPL LVGV PASE NPFK DKKP CIIL |
| Gene ID: | 2788 |
| Uniprot: | O60262 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| Calculated MW: | 7kDa |
| Observed MW: | 12kDa |
| Synonyms: | GNG7 |
| Background: |
| UniProt Protein Function: | G-gamma 7: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric gamma; G protein; G protein, heterotrimeric Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: plasma membrane; heterotrimeric G-protein complex Molecular Function:signal transducer activity Biological Process: regulation of adenylate cyclase activity; G-protein coupled receptor protein signaling pathway; synaptic transmission; behavioral fear response; receptor guanylyl cyclase signaling pathway; energy reserve metabolic process; locomotory behavior; regulation of G-protein coupled receptor protein signaling pathway |
| UniProt Code: | O60262 |
| NCBI GenInfo Identifier: | 32698769 |
| NCBI Gene ID: | 2788 |
| NCBI Accession: | NP_443079.1 |
| UniProt Secondary Accession: | O60262,B2R496, |
| UniProt Related Accession: | O60262 |
| Molecular Weight: | 7,522 Da |
| NCBI Full Name: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 |
| NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), gamma 7 |
| NCBI Official Symbol: | GNG7 |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 |
| UniProt Gene Name: | GNG7 |
| UniProt Entry Name: | GBG7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNG7 antibody (CAB10009) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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