Cell Biology Antibodies 12

Anti-GNG10 Antibody (CAB8423)

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SKU:
CAB8423
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GNG10 Antibody
Antibody SKU:CAB8423
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG10 (NP_001017998.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-251MG, HL-60, Mouse spleen, Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG10 (NP_001017998.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSSG ASAS ALQR LVEQ LKLE AGVE RIKV SQAA AELQ QYCM QNAC KDAL LVGV PAGS NPFR EPRS CALL
Gene ID:2790
Uniprot:P50151
Cellular Location:Cell membrane, Cytoplasmic side, Lipid-anchor
Calculated MW:7kDa
Observed MW:14kDa
Synonyms:GNG10
Background:
UniProt Protein Function:G-gamma 10: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3. Belongs to the G protein gamma family.
UniProt Protein Details:

Protein type:G protein, heterotrimeric; G protein, heterotrimeric gamma; G protein

Chromosomal Location of Human Ortholog: 9q31.3

Cellular Component: plasma membrane; heterotrimeric G-protein complex

Molecular Function:GTPase activity; signal transducer activity

Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; energy reserve metabolic process; signal transduction

UniProt Code:P50151
NCBI GenInfo Identifier:63055067
NCBI Gene ID:2790
NCBI Accession:NP_001017998.1
UniProt Secondary Accession:P50151,Q3B7K2, Q4VC27,
UniProt Related Accession:P50151
Molecular Weight:7,205 Da
NCBI Full Name:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
NCBI Synonym Full Names:guanine nucleotide binding protein (G protein), gamma 10
NCBI Official Symbol:GNG10  
NCBI Protein Information:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
UniProt Protein Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
UniProt Gene Name:GNG10  
UniProt Entry Name:GBG10_HUMAN
Anti-GNG10 Polyclonal Antibody (CAB8423)Western blot analysis of extracts of various cell lines, using GNG10 antibody (CAB8423) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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