Cell Biology Antibodies 12
Anti-GNG10 Antibody (CAB8423)
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- SKU:
- CAB8423
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GNG10 Antibody |
| Antibody SKU: | CAB8423 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG10 (NP_001017998.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, HL-60, Mouse spleen, Rat spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG10 (NP_001017998.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSSG ASAS ALQR LVEQ LKLE AGVE RIKV SQAA AELQ QYCM QNAC KDAL LVGV PAGS NPFR EPRS CALL |
| Gene ID: | 2790 |
| Uniprot: | P50151 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| Calculated MW: | 7kDa |
| Observed MW: | 14kDa |
| Synonyms: | GNG10 |
| Background: |
| UniProt Protein Function: | G-gamma 10: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric; G protein, heterotrimeric gamma; G protein Chromosomal Location of Human Ortholog: 9q31.3 Cellular Component: plasma membrane; heterotrimeric G-protein complex Molecular Function:GTPase activity; signal transducer activity Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; energy reserve metabolic process; signal transduction |
| UniProt Code: | P50151 |
| NCBI GenInfo Identifier: | 63055067 |
| NCBI Gene ID: | 2790 |
| NCBI Accession: | NP_001017998.1 |
| UniProt Secondary Accession: | P50151,Q3B7K2, Q4VC27, |
| UniProt Related Accession: | P50151 |
| Molecular Weight: | 7,205 Da |
| NCBI Full Name: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 |
| NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), gamma 10 |
| NCBI Official Symbol: | GNG10 |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 |
| UniProt Gene Name: | GNG10 |
| UniProt Entry Name: | GBG10_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNG10 antibody (CAB8423) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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