Cell Biology Antibodies 9

Anti-GNB5 Antibody (CAB4447)

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SKU:
CAB4447
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
GNB5
Synonyms:
GB5
Synonyms:
IDDCA
Synonyms:
LADCI
Research Area:
Cell Biology

Description

Product Name:GNB5 Rabbit pAb
Product Code:CAB4447
Size:20uL, 50uL, 100uL
Synonyms:GNB5, GB5, IDDCA, LADCI
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, HL-60, 293T, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATE GLHE NETL ASLK SEAE SLKG KLEE ERAK LHDV ELHQ VAER VEAL GQFV MKTR RTLK GHGN KVLC MDWC KDKR RIVS SSQD GKVI VWDS FTTN KEHA VTMP CTWV MACA YAPS GCAI ACGG LDNK CSVY PLTF DKNE NMAA KKKS VAMH TNYL SACS FTNS DMQI LTAS GDGT CALW DVES GQLL QSFH GHGA DVLC
Gene ID:10681
Uniprot:O14775
Calculated MW:31kDa/38kDa/43kDa
Observed MW:39kDa
UniProt Protein Function:G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:G protein, heterotrimeric beta

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: plasma membrane; nucleus

Molecular Function:GTPase activity; G-protein gamma-subunit binding; signal transducer activity; protein binding; chaperone binding

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction

NCBI Summary:Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
UniProt Code:O14775
NCBI GenInfo Identifier:38258891
NCBI Gene ID:10681
NCBI Accession:O14775.2
UniProt Secondary Accession:O14775,Q9HAU9, Q9UFT3, B2RBR5,
UniProt Related Accession:O14775
Molecular Weight:395
NCBI Full Name:Guanine nucleotide-binding protein subunit beta-5
NCBI Synonym Full Names:guanine nucleotide binding protein (G protein), beta 5
NCBI Official Symbol:GNB5  
NCBI Official Synonym Symbols:GB5  
NCBI Protein Information:guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L
UniProt Protein Name:Guanine nucleotide-binding protein subunit beta-5
UniProt Synonym Protein Names:Gbeta5; Transducin beta chain 5
Protein Family:Guanine nucleotide-binding protein
UniProt Gene Name:GNB5  
UniProt Entry Name:GBB5_HUMAN
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