Cell Biology Antibodies 1
Anti-GNAZ Antibody (CAB0605)
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- SKU:
- CAB0605
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GNAZ Antibody |
| Antibody SKU: | CAB0605 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human GNAZ (NP_002064.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human GNAZ (NP_002064.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGCR QSSE EKEA ARRS RRID RHLR SESQ RQRR EIKL LLLG TSNS GKST IVKQ MKII HSGG FNLE ACKE YKPL IIYN AIDS LTRI IRAL AALR IDFH NPDR AYDA VQLF ALTG PAES KGEI TPEL LGVM RRLW ADPG AQAC FSRS SEYH LEDN AAYY LNDL ERIA AADY IPTV EDIL RSRD MTTG IVEN KFTF KELT FKMV DVGG QRSE RKKW IHCF EGVT AIIF CVEL SGYD LKLY EDNQ TSRM AESL RLFD SICN NNWF INTS LILF LNKK DLLA EKIR RIPL TICF PEYK GQNT YEEA AVYI QRQF EDLN RNKE TKEI YSHF TCAT DTSN IQFV FDAV TDVI IQNN LKYI GLC |
| Gene ID: | 2781 |
| Uniprot: | P19086 |
| Cellular Location: | Lipid-anchor, Membrane |
| Calculated MW: | 40kDa |
| Observed MW: | 40kDa |
| Synonyms: | GNAZ, gz-alpha |
| Background: | The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. |
| UniProt Protein Function: | G-alpha(z): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily. |
| UniProt Protein Details: | Protein type:Nuclear envelope; Endoplasmic reticulum; G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z)) Chromosomal Location of Human Ortholog: 22q11.22 Cellular Component: endoplasmic reticulum; plasma membrane; heterotrimeric G-protein complex; nuclear envelope; cytosol Molecular Function:GTPase activity; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; receptor signaling protein activity; metabotropic serotonin receptor binding Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway |
| NCBI Summary: | The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P19086 |
| NCBI GenInfo Identifier: | 121005 |
| NCBI Gene ID: | 2781 |
| NCBI Accession: | P19086.3 |
| UniProt Secondary Accession: | P19086,Q4QRJ6, B2R6C1, |
| UniProt Related Accession: | P19086 |
| Molecular Weight: | 355 |
| NCBI Full Name: | Guanine nucleotide-binding protein G(z) subunit alpha |
| NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| NCBI Official Symbol: | GNAZ |
| NCBI Protein Information: | guanine nucleotide-binding protein G(z) subunit alpha; guanine nucleotide-binding protein G(z) subunit alpha; gz-alpha; g(x) alpha chain; transducin alpha |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(z) subunit alpha |
| UniProt Synonym Protein Names: | G(x) alpha chain; Gz-alpha |
| UniProt Gene Name: | GNAZ |
| UniProt Entry Name: | GNAZ_HUMAN |
 | Western blot analysis of extracts of mouse brain, using GNAZ antibody (CAB0605). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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