Cell Biology Antibodies 4
Anti-GNA12 Antibody (CAB13740)
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- SKU:
- CAB13740
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GNA12 Antibody |
| Antibody SKU: | CAB13740 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNA12 (NP_031379.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse pancreas, Rat pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNA12 (NP_031379.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSGV VRTL SRCL LPAE AGGA RERR AGSG ARDA EREA RRRS RDID ALLA RERR AVRR LVKI LLLG AGES GKST FLKQ MRII HGRE FDQK ALLE FRDT IFDN ILKG SRVL VDAR DKLG IPWQ YSEN EKHG MFLM AFEN KAGL PVEP ATFQ LYVP ALSA LWRD SGIR EAFS RRSE FQLG ESVK YFLD NLDR IGQL NYFP SKQD |
| Gene ID: | 2768 |
| Uniprot: | Q03113 |
| Cellular Location: | Lipid-anchor, Membrane |
| Calculated MW: | 34kDa/37kDa/44kDa |
| Observed MW: | 44kDa |
| Synonyms: | GNA12, NNX3, RMP, gep |
| Background: |
| UniProt Protein Function: | G-alpha 12: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(12) subfamily. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric alpha G(12); G protein, heterotrimeric; G protein Chromosomal Location of Human Ortholog: 7p22.2 Cellular Component: brush border membrane; focal adhesion; heterotrimeric G-protein complex; plasma membrane Molecular Function:D5 dopamine receptor binding; G-protein beta/gamma-subunit binding; GTPase activity; protein binding; signal transducer activity Biological Process: blood coagulation; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; platelet activation; regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of TOR signaling pathway; Rho protein signal transduction |
| UniProt Code: | Q03113 |
| NCBI GenInfo Identifier: | 38258934 |
| NCBI Gene ID: | 2768 |
| NCBI Accession: | Q03113.4 |
| UniProt Secondary Accession: | Q03113,Q2T9L1, Q5PPR5, Q86UM8, Q8TD71, Q9UDU9, A4D204 B3KXS2, B7Z3F7, |
| UniProt Related Accession: | Q03113 |
| Molecular Weight: | 34,002 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein subunit alpha-12 |
| NCBI Synonym Full Names: | G protein subunit alpha 12 |
| NCBI Official Symbol: | GNA12 |
| NCBI Official Synonym Symbols: | RMP; gep; NNX3 |
| NCBI Protein Information: | guanine nucleotide-binding protein subunit alpha-12 |
| UniProt Protein Name: | Guanine nucleotide-binding protein subunit alpha-12 |
| Protein Family: | Guanine nucleotide-binding protein |
| UniProt Gene Name: | GNA12 |
| UniProt Entry Name: | GNA12_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNA12 antibody (CAB13740) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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