Signal Transduction Antibodies 3
Anti-GLUT3 Antibody (CAB4137)
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- SKU:
- CAB4137
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-GLUT3 Antibody |
| Antibody SKU: | CAB4137 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GLUT3 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Jurkat, SH-SY5Y, Mouse testis, Mouse brain, Rat testis, Rat brain |
| Immunogen: | A synthesized peptide derived from human GLUT3 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6515 |
| Uniprot: | P11169 |
| Cellular Location: | |
| Calculated MW: | 54kDa |
| Observed MW: | 48-60KDa |
| Synonyms: | GLUT3 |
| Background: |
| UniProt Protein Function: | GLUT3: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. It???s surface expression is induced by insulin. It is restricted in humans to brain, testis (in the spermatozoa), and skeletal muscle, mostly in triads of slow-twitch fibres. Detected only in the brain of mouse and rat. IHC demonstrates its present in neurons, mainly at the plasma membrane, and to a lesser extent on intracellular vesicles distinct from synaptic vesicles. Present in the a-granules of human platelets, where it is translocated to the cell surface in response to thrombin stimulation. Its surface expression is increased by insulin or insulin growth-factor in cultured L6 muscle cells. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.3 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose binding; glucose transmembrane transporter activity Biological Process: glucose transport; L-ascorbic acid metabolic process |
| UniProt Code: | P11169 |
| NCBI GenInfo Identifier: | 121760 |
| NCBI Gene ID: | 6515 |
| NCBI Accession: | P11169.1 |
| UniProt Secondary Accession: | P11169,Q6I9U2, Q9UG15, B2R606, D3DUU6, |
| UniProt Related Accession: | P11169 |
| Molecular Weight: | 53924 Da |
| NCBI Full Name: | Solute carrier family 2, facilitated glucose transporter member 3 |
| NCBI Synonym Full Names: | solute carrier family 2 member 3 |
| NCBI Official Symbol: | SLC2A3 |
| NCBI Official Synonym Symbols: | GLUT3 |
| NCBI Protein Information: | solute carrier family 2, facilitated glucose transporter member 3 |
| UniProt Protein Name: | Solute carrier family 2, facilitated glucose transporter member 3 |
| UniProt Synonym Protein Names: | Glucose transporter type 3, brain; GLUT-3 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC2A3 |
| UniProt Entry Name: | GTR3_HUMAN |
 | Western blot - GLUT3 Rabbit mAb (CAB4137) |
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