Cell Biology Antibodies 17
Anti-GLUR Antibody (CAB4566)
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- SKU:
- CAB4566
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GLUR Antibody |
| Antibody SKU: | CAB4566 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GLUR |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, A-549, K-562, Mouse liver, Mouse brain, Mouse kidney, Rat lung, Rat liver, Rat kidney |
| Immunogen: | A synthesized peptide derived from human GLUR |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2936 |
| Uniprot: | P00390 |
| Cellular Location: | |
| Calculated MW: | 56kDa |
| Observed MW: | 56KDa |
| Synonyms: | HEL-75, HEL-S-122m |
| Background: | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] |
| UniProt Protein Function: | GSR: a class-I pyridine nucleotide-disulfide oxidoreductase. Maintains high levels of reduced glutathione in the cytosol. Alternative initiation results in a mitochondrial and a cytoplasmic isoform. |
| UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - glutathione; Oxidoreductase; EC 1.8.1.7 Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: cytosol; mitochondrial matrix Molecular Function:electron carrier activity; glutathione-disulfide reductase activity Biological Process: nucleobase, nucleoside and nucleotide interconversion; response to reactive oxygen species |
| NCBI Summary: | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] |
| UniProt Code: | P00390 |
| NCBI GenInfo Identifier: | 14916998 |
| NCBI Gene ID: | 2936 |
| NCBI Accession: | P00390.2 |
| UniProt Secondary Accession: | P00390,Q7Z5C9, Q9NP63, C8KIL8, C8KIL9, C8KIM0, D3DSV3 |
| UniProt Related Accession: | P00390 |
| Molecular Weight: | 47,267 Da |
| NCBI Full Name: | Glutathione reductase, mitochondrial |
| NCBI Synonym Full Names: | glutathione-disulfide reductase |
| NCBI Official Symbol: | GSR |
| NCBI Official Synonym Symbols: | HEL-75; HEL-S-122m |
| NCBI Protein Information: | glutathione reductase, mitochondrial |
| UniProt Protein Name: | Glutathione reductase, mitochondrial |
| Protein Family: | Glutathione reductase |
| UniProt Gene Name: | GSR |
| UniProt Entry Name: | GSHR_HUMAN |
 | Western blot - GLUR Rabbit mAb (CAB4566) |
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