Cell Biology Antibodies 14

Anti-GLI2 Antibody (CAB16864)

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SKU:
CAB16864
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-GLI2 Antibody
Antibody SKU:CAB16864
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of mouse GLI2.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:293T, MCF7, HeLa, NIH/3T3
Immunogen:Recombinant protein of mouse GLI2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:14633
Uniprot:Q0VGT2
Cellular Location:Cytoplasm, Nucleus
Calculated MW:168kDa
Observed MW:170kDa
Anti-GLI2 Antibody (CAB16864)Western blot - GLI2 Rabbit pAb (CAB16864)
Synonyms:GLI2, CJS, HPE9, PHS2, THP1, THP2, Gli2
Background:This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
UniProt Code:Q0VGT2
NCBI GenInfo Identifier:124487481
NCBI Gene ID:14633
NCBI Accession:NP_001074594.1
UniProt Related Accession:Q0VGT2
Molecular Weight:90kDa
NCBI Full Name:zinc finger protein GLI2
NCBI Synonym Full Names:GLI-Kruppel family member GLI2
NCBI Official Symbol:Gli2  
NCBI Protein Information:zinc finger protein GLI2
UniProt Protein Name:Zinc finger protein GLI2
UniProt Synonym Protein Names:Tax helper protein
Protein Family:Zinc finger protein
UniProt Gene Name:Gli2  
UniProt Entry Name:GLI2_MOUSE
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