Anti-GJA8 Antibody (CAB19312)
- SKU:
- CAB19312
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CAE
- Synonyms:
- CAE1
- Synonyms:
- CTRCT1
- Synonyms:
- CX50
- Synonyms:
- CZP1
- Synonyms:
- MP70
- Synonyms:
- GJA8
Description
| Product Name: | GJA8 Rabbit pAb |
| Product Code: | CAB19312 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CAE, CAE1, CTRCT1, CX50, CZP1, MP70, GJA8 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human GJA8. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Raji |
| Immunogen: | Recombinant protein of human GJA8. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2703 |
| Uniprot: | P48165 |
| Observed MW: | 48kDa |
| UniProt Protein Function: | GJA8: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. Eye lens. Belongs to the connexin family. Alpha-type (group II) subfamily.Protein type: Membrane protein, integral; Channel, misc.; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1q21.1Cellular Component: integral to plasma membraneMolecular Function: channel activityBiological Process: transport; visual perceptionDisease: Cataract 1, Multiple Types; Chromosome 1q21.1 Deletion Syndrome, 1.35-mb |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009] |
| UniProt Code: | P48165 |
| NCBI GenInfo Identifier: | 13124697 |
| NCBI Gene ID: | 2703 |
| NCBI Accession: | P48165.3 |
| UniProt Secondary Accession: | P48165,Q5VVN9, Q9NP25, A7L5M5 |
| UniProt Related Accession: | P48165 |
| Molecular Weight: | 48,229 Da |
| NCBI Full Name: | Gap junction alpha-8 protein |
| NCBI Synonym Full Names: | gap junction protein alpha 8 |
| NCBI Official Symbol: | GJA8 |
| NCBI Official Synonym Symbols: | CAE; CAE1; CX50; CZP1; MP70; CTRCT1 |
| NCBI Protein Information: | gap junction alpha-8 protein |
| UniProt Protein Name: | Gap junction alpha-8 protein |
| UniProt Synonym Protein Names: | Connexin-50; Cx50; Lens fiber protein MP70 |
| Protein Family: | Gap junction alpha-8 protein |
| UniProt Gene Name: | GJA8 |
| UniProt Entry Name: | CXA8_HUMAN |
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