Name: Anti-GIMAP5 Antibody (CAB8684)
Brand: Cell Biology Antibodies 12
SKU: CAB8684
Availability: OutOfStock

Antibody Name:	Anti-GIMAP5 Antibody
Antibody SKU:	CAB8684
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse kidney, Rat spleen

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	WGSV EEQR QQQA ELLA VIER LGRE REGS FHSN DLFL DAQL LQRT GAGA CQED YRQY QAKV EWQV EKHK QELR ENES NWAY K
Gene ID:	55340
Uniprot:	Q96F15
Cellular Location:	Lysosome, Mitochondrion outer membrane, Single-pass type IV membrane protein
Calculated MW:	34kDa/39kDa
Observed MW:	34kDa

Synonyms:

GIMAP5, HIMAP3, IAN-5, IAN4, IAN4L1, IAN5, IMAP3, IROD

Background:

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

UniProt Protein Function:	GIMAP5: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence. Belongs to the IAN GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Hydrolase; Apoptosis; Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: mitochondrial outer membrane; lysosome; integral to membrane Molecular Function:GTP binding
NCBI Summary:	This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010]
UniProt Code:	Q96F15
NCBI GenInfo Identifier:	28416949
NCBI Gene ID:	55340
NCBI Accession:	NP_060854.2
UniProt Secondary Accession:	Q96F15,Q6IA75, Q96NE4, Q9NUK9, D3DWZ5,
UniProt Related Accession:	Q96F15
Molecular Weight:	34,846 Da
NCBI Full Name:	GTPase IMAP family member 5
NCBI Synonym Full Names:	GTPase, IMAP family member 5
NCBI Official Symbol:	GIMAP5
NCBI Official Synonym Symbols:	IAN4; IAN5; IROD; IAN-5; IMAP3; HIMAP3; IAN4L1
NCBI Protein Information:	GTPase IMAP family member 5; immunity associated protein 3; immune associated nucleotide 4 like 1; immunity-associated nucleotide 5 protein; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5
UniProt Protein Name:	GTPase IMAP family member 5
UniProt Synonym Protein Names:	Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; IAN-5; hIAN5; Immunity-associated protein 3
Protein Family:	GTPase IMAP family
UniProt Gene Name:	GIMAP5
UniProt Entry Name:	GIMA5_HUMAN

Anti-GIMAP5 Polyclonal Antibody (CAB8684)

Western blot analysis of extracts of various cell lines, using GIMAP5 antibody (CAB8684) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

Antibodies

GIMAP5 Antibody (PACO00853)

GIMAP5 Antibody (PACO09467)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)