Description
| Product Name: | GCET2 Rabbit mAb |
| Product Code: | CAB19823 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GCAT2, GCET2, HGAL |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GCET2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Raji, Mouse spleen, Rat spleen |
| Immunogen: | A synthesized peptide derived from human GCET2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 257144 |
| Uniprot: | Q8N6F7 |
| Calculated MW: | kDa |
| Observed MW: | 21KDa |
| UniProt Protein Function: | GCET2: a protein expressed in normal germinal center B cells, immature B and T cells. Induced by IL4. Its expression strongly predicts survival in diffuse large B-cell lymphoma. Protein type: Unknown functionChromosomal Location of Human Ortholog: 3q13.2Molecular Function: actin binding; myosin II binding; protein binding; protein kinase bindingBiological Process: regulation of B cell receptor signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N6F7 |
| NCBI GenInfo Identifier: | 74729123 |
| NCBI Gene ID: | 257144 |
| NCBI Accession: | Q8N6F7.1 |
| UniProt Secondary Accession: | Q8N6F7,C9JD17, C9JUG6 |
| UniProt Related Accession: | Q8N6F7 |
| Molecular Weight: | 19,206 Da |
| NCBI Full Name: | Germinal center-associated signaling and motility protein |
| NCBI Synonym Full Names: | germinal center associated signaling and motility |
| NCBI Official Symbol: | GCSAM |
| NCBI Official Synonym Symbols: | HGAL; GCAT2; GCET2 |
| NCBI Protein Information: | germinal center-associated signaling and motility protein |
| UniProt Protein Name: | Germinal center-associated signaling and motility protein |
| UniProt Synonym Protein Names: | Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; hGAL |
| Protein Family: | |
| UniProt Gene Name: | GCSAM |
| UniProt Entry Name: |