| UniProt Protein Function: | GCET2: a protein expressed in normal germinal center B cells, immature B and T cells. Induced by IL4. Its expression strongly predicts survival in diffuse large B-cell lymphoma. Protein type: Unknown functionChromosomal Location of Human Ortholog: 3q13.2Molecular Function: actin binding; myosin II binding; protein binding; protein kinase bindingBiological Process: regulation of B cell receptor signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N6F7 |
| NCBI GenInfo Identifier: | 74729123 |
| NCBI Gene ID: | 257144 |
| NCBI Accession: | Q8N6F7.1 |
| UniProt Secondary Accession: | Q8N6F7,C9JD17, C9JUG6 |
| UniProt Related Accession: | Q8N6F7 |
| Molecular Weight: | 19,206 Da |
| NCBI Full Name: | Germinal center-associated signaling and motility protein |
| NCBI Synonym Full Names: | germinal center associated signaling and motility |
| NCBI Official Symbol: | GCSAM |
| NCBI Official Synonym Symbols: | HGAL; GCAT2; GCET2 |
| NCBI Protein Information: | germinal center-associated signaling and motility protein |
| UniProt Protein Name: | Germinal center-associated signaling and motility protein |
| UniProt Synonym Protein Names: | Germinal center B-cell-expressed transcript 2 protein; Germinal center-associated lymphoma protein; hGAL |
| Protein Family: | |
| UniProt Gene Name: | GCSAM |
| UniProt Entry Name: | |
