Epigenetics & Nuclear Signaling Antibodies 2

Anti-GBX2 Antibody (CAB14733)

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SKU:
CAB14733
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-GBX2 Antibody
Antibody SKU:CAB14733
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GBX2 (NP_001476.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, SH-SY5Y
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GBX2 (NP_001476.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSAA FPPS LMMM QRPL GSST AFSI DSLI GSPP QPSP GHFV YTGY PMFM PYRP VVLP PPPP PPPA LPQA ALQP ALPP AHPH HQIP SLPT GFCS SLAQ GMAL TSTL MATL PGGF SASP QHQE AAAA RKFA PQPL PGGG NFDK AEAL QADA EDGK GFLA KEGS LLAF SAAE TVQA SLVG AVRG QGKD ESKV EDDP KGKE ESFS LESD VDYS SDDN LTGQ AAHK EEDP GHAL EETP PSSG AAGS TTST GKNR RR
Gene ID:2637
Uniprot:P52951
Cellular Location:Nucleus
Calculated MW:37kDa
Observed MW:34KDa
Synonyms:GBX2
Background:
UniProt Protein Function:GBX2: May act as a transcription factor for cell pluripotency and differentiation in the embryo.
UniProt Protein Details:

Protein type:DNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q37.2

Cellular Component: nucleus

Molecular Function:sequence-specific DNA binding; transcription factor activity

Biological Process: axon guidance; midbrain-hindbrain boundary morphogenesis; nervous system development; autonomic nervous system development; inner ear morphogenesis; granule cell precursor proliferation; transcription, DNA-dependent; thalamus development; patterning of blood vessels; regulation of transcription, DNA-dependent; forebrain neuron development; rhombomere 2 development; cerebellum development; neural crest cell migration

UniProt Code:P52951
NCBI GenInfo Identifier:45593144
NCBI Gene ID:2637
NCBI Accession:NP_001476
UniProt Related Accession:P52951
Molecular Weight:37kDa
NCBI Full Name:homeobox protein GBX-2 isoform 1
NCBI Synonym Full Names:gastrulation brain homeobox 2
NCBI Official Symbol:GBX2  
NCBI Protein Information:homeobox protein GBX-2
UniProt Protein Name:Homeobox protein GBX-2
UniProt Synonym Protein Names:Gastrulation and brain-specific homeobox protein 2
Protein Family:Homeobox protein
UniProt Gene Name:GBX2  
UniProt Entry Name:GBX2_HUMAN
Anti-GBX2 Antibody (CAB14733)Western blot analysis of extracts of various cell lines, using GBX2 antibody (CAB14733) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-GBX2 Antibody (CAB14733)Immunofluorescence analysis of C6 cells using GBX2 antibody (CAB14733) at dilution of 1:100. Blue: DAPI for nuclear staining.
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