Immunology Antibodies 2
Anti-GBP5 Antibody (CAB17346)
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- SKU:
- CAB17346
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-GBP5 Antibody |
| Antibody SKU: | CAB17346 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human GBP5 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human GBP5 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 115362 |
| Uniprot: | Q96PP8 |
| Cellular Location: | Cytoplasm, Golgi apparatus membrane, Lipid-anchor |
| Calculated MW: | 55kDa/66kDa |
| Observed MW: | Refer to figures |
| Synonyms: | GBP5, GBP-5 |
| Background: | This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | GBP5: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Hydrolase; Vesicle Chromosomal Location of Human Ortholog: 1p22.2 Cellular Component: membrane Molecular Function:identical protein binding; protein binding Biological Process: interleukin-1 beta secretion; positive regulation of innate immune response; protein homotetramerization |
| UniProt Code: | Q96PP8 |
| NCBI GenInfo Identifier: | 37999757 |
| NCBI Gene ID: | 115362 |
| NCBI Accession: | Q96PP8.1 |
| UniProt Secondary Accession: | Q96PP8,Q86TM5, B2RCE1, |
| UniProt Related Accession: | Q96PP8 |
| Molecular Weight: | 55,247 Da |
| NCBI Full Name: | Guanylate-binding protein 5 |
| NCBI Synonym Full Names: | guanylate binding protein 5 |
| NCBI Official Symbol: | GBP5 |
| NCBI Official Synonym Symbols: | GBP-5 |
| NCBI Protein Information: | guanylate-binding protein 5 |
| UniProt Protein Name: | Guanylate-binding protein 5 |
| UniProt Synonym Protein Names: | GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5 |
| Protein Family: | Guanylate-binding protein |
| UniProt Gene Name: | GBP5 |
| UniProt Entry Name: | GBP5_HUMAN |
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