Cell Biology Antibodies 5
Anti-GAST Antibody (CAB14571)
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- SKU:
- CAB14571
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-GAST Antibody |
| Antibody SKU: | CAB14571 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GAST (NP_000796.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse stomach |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GAST (NP_000796.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MQRL CVYV LIFA LALA AFSE ASWK PRSQ QPDA PLGT GANR DLEL PWLE QQGP ASHH RRQL GPQG PPHL VADP SKKQ GPWL EEEE EAYG WMDF GRRS AEDE |
| Gene ID: | 2520 |
| Uniprot: | P01350 |
| Cellular Location: | Secreted |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
| Synonyms: | GAST, GAS, gastrin |
| Background: | Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. |
| UniProt Protein Function: | gastrin: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Belongs to the gastrin/cholecystokinin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 17q21 Cellular Component: extracellular region; extracellular space Molecular Function:hormone activity; protein binding Biological Process: G-protein coupled receptor protein signaling pathway; response to food; signal transduction |
| NCBI Summary: | Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P01350 |
| NCBI GenInfo Identifier: | 120952 |
| NCBI Gene ID: | 2520 |
| NCBI Accession: | P01350.1 |
| UniProt Secondary Accession: | P01350,P78463, P78464, |
| UniProt Related Accession: | P01350,AAB19304 |
| Molecular Weight: | |
| NCBI Full Name: | Gastrin |
| NCBI Synonym Full Names: | gastrin |
| NCBI Official Symbol: | GAST |
| NCBI Official Synonym Symbols: | GAS |
| NCBI Protein Information: | gastrin |
| UniProt Protein Name: | Gastrin |
| UniProt Synonym Protein Names: | Gastrin-71Alternative name(s):Gastrin component I |
| Protein Family: | Gastrin |
| UniProt Gene Name: | GAST |
| UniProt Entry Name: | GAST_HUMAN |
 | Western blot analysis of extracts of mouse stomach, using GAST antibody (CAB14571) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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