Cell Biology Antibodies 7

Anti-GANC Antibody (CAB16377)

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SKU:
CAB16377
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-GANC Antibody
Antibody SKU:CAB16377
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GANC (NP_937784.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GANC (NP_937784.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DVLT SKPS TVRL ISCS GDTG SLIL ADGK GDLK CHIT ANPF KVDL VSEE EVVI SINS LGQL YFEH LQIL HKQR AAKE NEEE TSVD TSQE NQED LGLW EEKF G
Gene ID:2595
Uniprot:Q8TET4
Cellular Location:
Calculated MW:104kDa
Observed MW:104kDa
Synonyms:GANC
Background:Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1, 4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:GANC: Has alpha-glucosidase activity. Belongs to the glycosyl hydrolase 31 family.
UniProt Protein Details:

Protein type:EC 3.2.1.20; Hydrolase; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - galactose

Chromosomal Location of Human Ortholog: 15q15.2

NCBI Summary:Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]
UniProt Code:Q8TET4
NCBI GenInfo Identifier:296439340
NCBI Gene ID:2595
NCBI Accession:Q8TET4.3
UniProt Secondary Accession:Q8TET4,Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5,
UniProt Related Accession:Q8TET4
Molecular Weight:104,334 Da
NCBI Full Name:Neutral alpha-glucosidase C
NCBI Synonym Full Names:glucosidase alpha, neutral C
NCBI Official Symbol:GANC  
NCBI Protein Information:neutral alpha-glucosidase C
UniProt Protein Name:Neutral alpha-glucosidase C
Protein Family:Neutral alpha-glucosidase
UniProt Gene Name:GANC  
UniProt Entry Name:GANC_HUMAN
Anti-GANC Antibody (CAB16377)Western blot analysis of extracts of various cell lines, using GANC Rabbit pAb (CAB16377) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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