KO Validated Antibodies 2

Anti-GANAB Antibody (CAB19876)[KO Validated]

(No reviews yet) Write a Review
SKU:
CAB19876
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-GANAB Antibody [KO Validated]
Antibody SKU:CAB19876
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human GANAB.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa
Immunogen:Recombinant protein of human GANAB.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:23193
Uniprot:Q14697
Cellular Location:Endoplasmic reticulum, Golgi apparatus, Melanosome
Calculated MW:5kDa/106kDa/109kDa
Observed MW:98KDa
Anti-GANAB Antibody [KO Validated] (CAB19876)Western blot analysis of extracts from normal (control) and GANAB knockout (KO) HeLa cells, using GANAB antibody (CAB19876) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1S.
Synonyms:GANAB, G2AN, GIIA, GLUII, PKD3
Background:This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
UniProt Code:Q14697
NCBI GenInfo Identifier:38202257
NCBI Gene ID:23193
NCBI Accession:NP_938148
UniProt Secondary Accession:Q14697,Q8WTS9, Q9P0X0, A6NC20,
UniProt Related Accession:Q14697
Molecular Weight:5,673 Da
NCBI Full Name:neutral alpha-glucosidase AB isoform 2
NCBI Synonym Full Names:glucosidase, alpha; neutral AB
NCBI Official Symbol:GANAB  
NCBI Official Synonym Symbols:G2AN; GLUII  
NCBI Protein Information:neutral alpha-glucosidase AB; HEL-S-164nA; alpha glucosidase II alpha subunit; alpha-glucosidase 2; epididymis secretory sperm binding protein Li 164nA; glucosidase II subunit alpha
UniProt Protein Name:
Protein Family:Neutral alpha-glucosidase
UniProt Gene Name:
View AllClose

0 Reviews

View AllClose

Related Products