Description
Product Name: | GALNT4 Rabbit pAb |
Product Code: | CAB4243 |
Size: | 50uL, 100uL |
Synonyms: | GALNT4, GALNAC-T4, GALNACT4 |
Applications: | WB |
Reactivity: | Human, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human GALNT4. |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human, Rat |
Positive Samples: | HeLa, Rat brain |
Immunogen: | Recombinant protein of human GALNT4. |
Purification Method: | Affinity purification |
Storage: | Store at 4°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 8693 |
Uniprot: | Q8N4A0 |
Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
Calculated MW: | 45kDa/66kDa |
Observed MW: | 67KDa |
UniProt Protein Function: | GALNT4: an enzyme that catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane. |
UniProt Protein Details: | Protein type:Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral; EC 2.4.1.41; Transferase Chromosomal Location of Human Ortholog: 12q21.33 Cellular Component: Golgi membrane; Golgi apparatus; perinuclear region of cytoplasm; integral to membrane Molecular Function:metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; carbohydrate metabolic process; post-translational protein modification |
NCBI Summary: | This locus represents naturally occurring transcripts that splice the 5' exons of the POC1B (POC1 centriolar protein homolog B) gene on chromosome 12 to the GALNT4 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4) gene, which is located within a POC1B intron. Alternative splicing results in two transcript variants, one of which encodes a fusion isoform that shares sequence identity with the products of each individual gene. [provided by RefSeq, Dec 2010] |
UniProt Code: | Q8N4A0 |
NCBI GenInfo Identifier: | 338817878 |
NCBI Gene ID: | 100528030 |
NCBI Accession: | Q8N4A0.2 |
UniProt Secondary Accession: | Q8N4A0,O00208, B2R775, B4DMX6, |
Molecular Weight: | 578 |
NCBI Full Name: | Polypeptide N-acetylgalactosaminyltransferase 4 |
NCBI Synonym Full Names: | POC1B-GALNT4 readthrough |
NCBI Official Symbol: | POC1B-GALNT4 |
NCBI Protein Information: | POC1B-GALNT4 protein; POC1B-GALNT4 fusion |
UniProt Protein Name: | Polypeptide N-acetylgalactosaminyltransferase 4 |
UniProt Synonym Protein Names: | Polypeptide GalNAc transferase 4; GalNAc-T4; pp-GaNTase 4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4 |
Protein Family: | Polypeptide N-acetylgalactosaminyltransferase |
UniProt Gene Name: | GALNT4 |
UniProt Entry Name: | GALT4_HUMAN |