Metabolism Antibodies 1
Anti-GALM Antibody (CAB14362)
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- SKU:
- CAB14362
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-GALM Antibody |
| Antibody SKU: | CAB14362 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | OVCAR3, U-87MG, HepG2, A-431, Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASV TRAV FGEL PSGG GTVE KFQL QSDL LRVD IISW GCTI TALE VKDR QGRA SDVV LGFA ELEG YLQK QPYF GAVI GRVA NRIA KGTF KVDG KEYH LAIN KEPN SLHG GVRG FDKV LWTP RVLS NGVQ FSRI SPDG EEGY PGEL KVWV TYTL DGGE LIVN YRAQ ASQA TPVN LTNH SYFN LAGQ ASPN INDH EVTI EADT YLPV DETL IPTG EVAP VQGT AFDL RKPV ELGK HLQD FHLN GFDH NFCL KGSK EKHF CARV HHAA SGRV LEVY TTQP GVQF YTGN FLDG TLKG KNGA VYPK HSGF CLET QNWP DAVN QPRF PPVL LRPG EEYD HTTW FKFS VA |
| Gene ID: | 130589 |
| Uniprot: | Q96C23 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 37kDa |
| Observed MW: | 38kDa |
| Synonyms: | GALM, BLOCK25, GLAT, HEL-S-63p, IBD1 |
| Background: | This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose. |
| UniProt Protein Function: | GALM: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. Belongs to the aldose epimerase family. |
| UniProt Protein Details: | Protein type:EC 5.1.3.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase Chromosomal Location of Human Ortholog: 2p22.1 Cellular Component: cytoplasm Molecular Function:aldose 1-epimerase activity; carbohydrate binding Biological Process: galactose metabolic process; glucose metabolic process |
| NCBI Summary: | This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose.[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q96C23 |
| NCBI GenInfo Identifier: | 20270355 |
| NCBI Gene ID: | 130589 |
| NCBI Accession: | NP_620156 |
| UniProt Related Accession: | Q96C23 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | aldose 1-epimerase |
| NCBI Synonym Full Names: | galactose mutarotase |
| NCBI Official Symbol: | GALM |
| NCBI Official Synonym Symbols: | GLAT; IBD1; BLOCK25; HEL-S-63p |
| NCBI Protein Information: | aldose 1-epimerase |
| UniProt Protein Name: | Aldose 1-epimerase |
| UniProt Synonym Protein Names: | Galactose mutarotase |
| Protein Family: | Aldose 1-epimerase |
| UniProt Gene Name: | GALM |
| UniProt Entry Name: | GALM_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GALM antibody (CAB14362) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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