Signal Transduction Antibodies 3
Anti-GABA A Receptor beta 2 Antibody (CAB11558)
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- SKU:
- CAB11558
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-GABA A Receptor beta 2 Antibody |
| Antibody SKU: | CAB11558 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GABA A Receptor beta 2 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, Mouse liver, Mouse brain, Mouse spleen, Rat liver, Rat brain |
| Immunogen: | A synthesized peptide derived from human GABA A Receptor beta 2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2561 |
| Uniprot: | P47870 |
| Cellular Location: | |
| Calculated MW: | 59kDa |
| Observed MW: | 59KDa |
 | Western blot - GABA A Receptor beta 2 Rabbit mAb (CAB11558) |
| Synonyms: | |
| Background: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
| NCBI Summary: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47870 |
| NCBI GenInfo Identifier: | 292495010 |
| NCBI Gene ID: | 2561 |
| NCBI Accession: | P47870.2 |
| UniProt Related Accession: | P47870 |
| Molecular Weight: | ~ 59kDa |
| NCBI Full Name: | Gamma-aminobutyric acid receptor subunit beta-2 |
| NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor subunit beta2 |
| NCBI Official Symbol: | GABRB2 |
| NCBI Official Synonym Symbols: | ICEE2 |
| NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-2 |
| UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-2 |
| UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-2 |
| UniProt Gene Name: | GABRB2 |
| UniProt Entry Name: | GBRB2_HUMAN |
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