Name: Anti-FXYD7 Antibody (CAB14895)
Brand: Signal Transduction Antibodies 2
SKU: CAB14895
Availability: OutOfStock

Antibody Name:	Anti-FXYD7 Antibody
Antibody SKU:	CAB14895
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human FXYD7 (NP_071289.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse, Rat
Positive Samples:	Mouse brain, Rat brain

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human FXYD7 (NP_071289.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MATP TQTP TKAP EEPD PFYY DYNT VQTV GMTL ATIL FLLG ILIV ISKK VKCR KADS RSES PTCK SCKS ELPS SAPG GGGV
Gene ID:	53822
Uniprot:	P58549
Cellular Location:	Membrane, Single-pass membrane protein
Calculated MW:	8kDa
Observed MW:	18kDa

Synonyms:	FXYD7
Background:

UniProt Protein Function:	FXYD7: This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Dec 2000]
UniProt Protein Details:	Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: plasma membrane Molecular Function:protein binding
NCBI Summary:	This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Dec 2000]
UniProt Code:	P58549
NCBI GenInfo Identifier:	20138168
NCBI Gene ID:	53822
NCBI Accession:	P58549.1
UniProt Related Accession:	P58549
Molecular Weight:	8,524 Da
NCBI Full Name:	FXYD domain-containing ion transport regulator 7
NCBI Synonym Full Names:	FXYD domain containing ion transport regulator 7
NCBI Official Symbol:	FXYD7
NCBI Protein Information:	FXYD domain-containing ion transport regulator 7
UniProt Protein Name:	FXYD domain-containing ion transport regulator 7
Protein Family:	FXYD domain-containing ion transport regulator
UniProt Gene Name:	FXYD7
UniProt Entry Name:	FXYD7_HUMAN

Western blot analysis of extracts of various cell lines, using FXYD7 antibody (CAB14895) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

Antibodies

FXYD7 Antibody (PACO09373)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)