Anti-FXYD3 Antibody (CAB20301)
- SKU:
- CAB20301
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MAT8
- Synonyms:
- PLML
Description
| Product Name: | FXYD3 Rabbit pAb |
| Product Code: | CAB20301 |
| Size: | 50uL, 100uL |
| Synonyms: | MAT8, PLML |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human FXYD3 (NP_005962.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human FXYD3 (NP_005962.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5349 |
| Uniprot: | Q14802 |
| Calculated MW: | 9kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | FXYD3: Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels. Belongs to the FXYD family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane Molecular Function: chloride channel activity; ATPase binding Biological Process: regulation of catalytic activity; chloride transport; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] |
| UniProt Code: | Q14802 |
| NCBI GenInfo Identifier: | 3024101 |
| NCBI Gene ID: | 5349 |
| NCBI Accession: | Q14802.1 |
| UniProt Secondary Accession: | Q14802,Q13211, Q6IB59, A6NDE0, C9JDU2, F5H174, F8WB34 |
| UniProt Related Accession: | Q14802 |
| Molecular Weight: | 87 |
| NCBI Full Name: | FXYD domain-containing ion transport regulator 3 |
| NCBI Synonym Full Names: | FXYD domain containing ion transport regulator 3 |
| NCBI Official Symbol: | FXYD3 |
| NCBI Official Synonym Symbols: | MAT8; PLML |
| NCBI Protein Information: | FXYD domain-containing ion transport regulator 3; phospholemman-like protein; mammary tumor 8 kDa protein; chloride conductance inducer protein Mat-8 |
| UniProt Protein Name: | FXYD domain-containing ion transport regulator 3 |
| UniProt Synonym Protein Names: | Chloride conductance inducer protein Mat-8; Mammary tumor 8 kDa protein; Phospholemman-like |
| Protein Family: | FXYD domain-containing ion transport regulator |
| UniProt Gene Name: | FXYD3 |
| UniProt Entry Name: | FXYD3_HUMAN |
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