Autophagy Antibodies
Anti-FUNDC1 Antibody (CAB16318)
- SKU:
- CAB16318
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Description
| Antibody Name: | Anti-FUNDC1 Antibody |
| Antibody SKU: | CAB16318 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FUNDC1 (NP_776155.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat thymus |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FUNDC1 (NP_776155.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VATQ IVMG GVTG WCAG FLFQ KVGK LAAT AVGG GFLL LQIA SHSG YVQI DWKR VEKD VNKA KRQI KKRA NKAA PEIN NLIE EATE FIKQ NIVI SSGF VGGF L |
| Gene ID: | 139341 |
| Uniprot: | Q8IVP5 |
| Cellular Location: | |
| Calculated MW: | 17kDa |
| Observed MW: | 20kDa |
| Synonyms: | FUNDC1 |
| Background: | This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. |
| UniProt Protein Function: | FUNDC1: Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control. Belongs to the FUN14 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: Xp11.3 Cellular Component: integral to mitochondrial outer membrane; mitochondrial outer membrane Molecular Function:protein binding Biological Process: mitochondrion degradation; response to hypoxia |
| NCBI Summary: | This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q8IVP5 |
| NCBI GenInfo Identifier: | 74750673 |
| NCBI Gene ID: | 139341 |
| NCBI Accession: | Q8IVP5.1 |
| UniProt Related Accession: | Q8IVP5 |
| Molecular Weight: | 17,178 Da |
| NCBI Full Name: | FUN14 domain-containing protein 1 |
| NCBI Synonym Full Names: | FUN14 domain containing 1 |
| NCBI Official Symbol: | FUNDC1 |
| NCBI Protein Information: | FUN14 domain-containing protein 1 |
| UniProt Protein Name: | FUN14 domain-containing protein 1 |
| Protein Family: | FUN14 domain-containing protein |
| UniProt Gene Name: | FUNDC1 |
| UniProt Entry Name: | FUND1_HUMAN |
 | Western blot analysis of extracts of rat thymus, using FUNDC1 antibody (CAB16318) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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