Cell Biology Antibodies 13

Anti-FUK Antibody (CAB17268)

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SKU:
CAB17268
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FUK Antibody
Antibody SKU:CAB17268
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 795-1084 of human FUK (NP_659496.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, Mouse brain, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 795-1084 of human FUK (NP_659496.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LLKA AFIC AGIV HVHS ELQL SEQL LRTF GGGF ELHT WSEL PHGS GLGT SSIL AGTA LAAL QRAA GRVV GTEA LIHA VLHL EQVL TTGG GWQD QVGG LMPG IKVG RSRA QLPL KVEV EEVT VPEG FVQK LNDH LLLV YTGK TRLA RNLL QDVL RSWY ARLP AVVQ NAHS LVRQ TEEC AEGF RQGS LPLL GQCL TSYW EQKK LMAP GCEP LTVR RMMD VLAP HVHG QSLA GAGG GGFL YLLT KEPQ QKEA LEAV LAKT EGLG NYSI HLVE VDTQ GLSL KLLG TEAS TCCP FP
Gene ID:197258
Uniprot:Q8N0W3
Cellular Location:
Calculated MW:117kDa/118kDa
Observed MW:117kDa
Anti-FUK Antibody (CAB17268)Western blot - FUK Rabbit pAb (CAB17268)
Synonyms:FUK, 1110046B12Rik
Background:The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
UniProt Protein Function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.
NCBI Summary:The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
UniProt Code:Q8N0W3
NCBI GenInfo Identifier:63175654
NCBI Gene ID:197258
NCBI Accession:NP_659496.2
UniProt Secondary Accession:Q8N0W3,Q5PSM3, Q5XKL6, Q6ZRA0, Q96MT9,
UniProt Related Accession:Q8N0W3
Molecular Weight:Observed: 117 kDaPredicted: 118 kDa
NCBI Full Name:L-fucose kinase
NCBI Synonym Full Names:fucokinase
NCBI Official Symbol:FUK  
NCBI Official Synonym Symbols:1110046B12Rik  
NCBI Protein Information:L-fucose kinase
UniProt Protein Name:L-fucose kinase
Protein Family:Fukutin
UniProt Gene Name:FUK  
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