Signal Transduction Antibodies 2

Anti-FSCN2 Antibody (CAB16508)

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SKU:
CAB16508
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-FSCN2 Antibody
Antibody SKU:CAB16508
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human FSCN2 (NP_036550.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPTN GLHQ VLKI QFGL VNDT DRYL TAES FGFK VNAS APSL KRKQ TWVL EPDP GQGT AVLL RSSH LGRY LSAE EDGR VACE AEQP GRDC RFLV LPQP DGRW VLRS EPHG RFFG GTED QLSC FATA VSPA ELWT VHLA IHPQ AHLL SVSR RRYV HLCP REDE MAAD GDKP WGVD ALLT LIFR SRRY CLKS CDSR YLRS DGRL VWEP EPRA CYTL EFKA GKLA FKDC DGHY LAPV GPAG TLKA GRNT RPGK DELF DLEE SHPQ VVLV AANH RYVS VRQG VNVS ANQD DELD HETF LMQI DQET KKCT FYSS TG
Gene ID:25794
Uniprot:O14926
Cellular Location:Cell projection, Cytoplasm, cytoskeleton, stereocilium
Calculated MW:55kDa/57kDa
Observed MW:55kDa
Synonyms:FSCN2, RFSN, RP30, fascin-2
Background:This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
NCBI Summary:This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O14926
NCBI GenInfo Identifier:6912626
NCBI Gene ID:25794
NCBI Accession:NP_036550.1
UniProt Related Accession:O14926
Molecular Weight:55kDa
NCBI Full Name:fascin-2 isoform 1
NCBI Synonym Full Names:fascin actin-bundling protein 2, retinal
NCBI Official Symbol:FSCN2  
NCBI Official Synonym Symbols:RFSN; RP30  
NCBI Protein Information:fascin-2
UniProt Protein Name:Fascin-2
UniProt Synonym Protein Names:Retinal fascin
Protein Family:Fascin
UniProt Gene Name:FSCN2  
Anti-FSCN2 Antibody (CAB16508)Western blot analysis of extracts of various cell lines, using FSCN2 antibody (CAB16508) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.
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