Cell Biology Antibodies 6

Anti-FRMD3 Antibody (CAB16025)

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SKU:
CAB16025
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-FRMD3 Antibody
Antibody SKU:CAB16025
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human FRMD3 (NP_777598.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human FRMD3 (NP_777598.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FRSS SVKS LSQE MRCT IRLL DDSE ISCH IQRE TKGQ FLID HICN YYSL LEKD YFGI RYVD PEKQ RHWL EPNK SIFK QMKT HPPY TMCF RVKF YPHE PLKI KEEL TRYL LYLQ IKRD IFHG RLLC SFSD AAYL GACI VQAE LGDY DPDE HPEN YISE FEIF PKQS QKLE RKIV EIHK NELR G
Gene ID:257019
Uniprot:A2A2Y4
Cellular Location:
Calculated MW:23kDa/40kDa/63kDa/68kDa
Observed MW:Refer to figures
Synonyms:FRMD3, 4.1O, EPB41L4O, EPB41LO, P410
Background:The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:FRMD3: Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytoskeletal; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q21.32

NCBI Summary:The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:A2A2Y4
NCBI GenInfo Identifier:166988475
NCBI Gene ID:257019
NCBI Accession:A2A2Y4.1
UniProt Secondary Accession:A2A2Y4,Q53EP2, Q5JV59, Q5VZA1, Q86WP8, Q8IZ44, Q8N3Y5 Q8N9L2, A8MQB0, B4DN14,
UniProt Related Accession:A2A2Y4
Molecular Weight:63,664 Da
NCBI Full Name:FERM domain-containing protein 3
NCBI Synonym Full Names:FERM domain containing 3
NCBI Official Symbol:FRMD3  
NCBI Official Synonym Symbols:4.1O; P410; EPB41LO; EPB41L4O  
NCBI Protein Information:FERM domain-containing protein 3
UniProt Protein Name:FERM domain-containing protein 3
UniProt Synonym Protein Names:Band 4.1-like protein 4O; Ovary type protein 4.1; 4.1O
Protein Family:FERM domain-containing protein
UniProt Gene Name:FRMD3  
UniProt Entry Name:FRMD3_HUMAN
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