Epigenetics & Nuclear Signaling Antibodies 2

Anti-FOXS1 Antibody (CAB14732)

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SKU:
CAB14732
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-FOXS1 Antibody
Antibody SKU:CAB14732
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-330 of human FOXS1 (NP_004109.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse testis, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-330 of human FOXS1 (NP_004109.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EGTR GPAK ARRG PLRA TSQD PGVP NATT GRQC SFPP ELPD PKGL SFGG LVGA MPAS MCPA TTDG RPRP PMEP KEIS TPKP ACPG ELPV ATSS SSCP AFGF PAGF SEAE SFNK APTP VLSP ESGI GSSY QCRL QALN FCMG ADPG LEHL LASA APSP APPT PPGS LRAP LPLP TDHK EPWV AGGF PVQG GSGY PLGL TPCL YRTP GMFF FE
Gene ID:2307
Uniprot:O43638
Cellular Location:Nucleus
Calculated MW:35kDa
Observed MW:35kDa
Synonyms:FOXS1, FKHL18, FREAC10
Background:The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown.
UniProt Protein Function:FKHL18: Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 20q11.21

Cellular Component: nucleus

Molecular Function:DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; blood vessel development; negative regulation of transcription factor activity; positive regulation of multicellular organism growth; neuromuscular process controlling balance; negative regulation of transcription, DNA-dependent

NCBI Summary:The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]
UniProt Code:O43638
NCBI GenInfo Identifier:57015282
NCBI Gene ID:2307
NCBI Accession:O43638.2
UniProt Secondary Accession:O43638,Q61574,
UniProt Related Accession:O43638
Molecular Weight:330
NCBI Full Name:Forkhead box protein S1
NCBI Synonym Full Names:forkhead box S1
NCBI Official Symbol:FOXS1  
NCBI Official Synonym Symbols:FKHL18; FREAC10  
NCBI Protein Information:forkhead box protein S1; FREAC-10; forkhead-like 18 protein; forkhead-related activator 10; forkhead-related transcription factor 10; forkhead-related transcription factor FREAC-10
UniProt Protein Name:Forkhead box protein S1
UniProt Synonym Protein Names:Forkhead-like 18 protein; Forkhead-related transcription factor 10; FREAC-10
Protein Family:Forkhead box protein
UniProt Gene Name:FOXS1  
UniProt Entry Name:FOXS1_HUMAN
Anti-FOXS1 Antibody (CAB14732)Western blot analysis of extracts of various cell lines, using FOXS1 antibody (CAB14732) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s.
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